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Anophthalmia-megalocornea-cardiopathy-skeletal anomalies syndrome

ORPHA:1101Malformation syndromeAutosomal recessiveInfancy, Neonatal

Фенотипы (28)

Частый (30–79%)28
HP:0000023Inguinal hernia
HP:0000028Cryptorchidism
HP:0000268Dolichocephaly
HP:0000303Mandibular prognathia
HP:0000327Hypoplasia of the maxilla
HP:0000343Long philtrum
HP:0000485Megalocornea
HP:0000526Aniridia
HP:0000528Anophthalmia
HP:0000545Myopia
HP:0000587Abnormal optic nerve morphology
HP:0000598Abnormality of the ear
HP:0000767Pectus excavatum
HP:0001131Corneal dystrophy
HP:0001357Plagiocephaly
HP:0001537Umbilical hernia
HP:0001653Mitral regurgitation
HP:0001704Tricuspid valve prolapse
HP:0001762Talipes equinovarus
HP:0002650Scoliosis
HP:0002705High, narrow palate
HP:0004327Abnormal vitreous humor morphology
HP:0005180Tricuspid regurgitation
HP:0009004Hypoplasia of the musculature
HP:0009465Ulnar deviation of finger
HP:0030680Abnormal cardiovascular system morphology
HP:0100490Camptodactyly of finger
HP:0200007Abnormal size of the palpebral fissures

Эпидемиология (2)

Cases/families
Worldwide
Point prevalence
<1 / 1 000 000
Worldwide

Лекарства и терапия

Источник: Open Targets Platform (в реальном времени)

Клинические исследования

Источник: ClinicalTrials.gov (в реальном времени)

Внешние ресурсы