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Arachnodactyly-abnormal ossification-intellectual disability syndrome

ORPHA:1129Malformation syndromeUnknownInfancy, Neonatal

Фенотипы (15)

Частый (30–79%)14
HP:0000270Delayed cranial suture closure
HP:0000347Micrognathia
HP:0000494Downslanted palpebral fissures
HP:0000586Shallow orbits
HP:0001166Arachnodactyly
HP:0001249Intellectual disability
HP:0001263Global developmental delay
HP:0002007Frontal bossing
HP:0003196Short nose
HP:0008947Floppy infant
HP:0010539Thin calvarium
HP:0010565Aplasia/Hypoplasia of the Epiglottis
HP:0011800Midface retrusion
HP:0011968Feeding difficulties
Периодический (5–29%)1
HP:0002104Apnea

Эпидемиология (2)

Cases/families
Worldwide
Point prevalence
<1 / 1 000 000
Worldwide

Лекарства и терапия

Источник: Open Targets Platform (в реальном времени)

Клинические исследования

Источник: ClinicalTrials.gov (в реальном времени)

Внешние ресурсы