Choanal atresia
ORPHA:137914Morphological anomalyNot applicableChildhood, Infancy, Neonatal
Фенотипы (HPO)16
Частый (30–79%)3
HP:0001742Nasal congestion
HP:0011109Chronic sinusitis
HP:0031416Abnormal nasal mucus secretion
Периодический (5–29%)12
HP:0000961Cyanosis
HP:0001363Craniosynostosis
HP:0001601Laryngomalacia
HP:0001607Subglottic stenosis
HP:0002098Respiratory distress
HP:0002205Recurrent respiratory infections
HP:0002779Tracheomalacia
HP:0002781Upper airway obstruction
HP:0005321Mandibulofacial dysostosis
HP:0011968Feeding difficulties
HP:0030215Inappropriate crying
HP:0030842Choking episodes
Очень редкий (1–4%)1
HP:0010442Polydactyly
Эпидемиология17
| Тип оценки | Класс распространённости | Среднее (на 100к) | Регион | Квалификация |
|---|---|---|---|---|
| Prevalence at birth | 1-9 / 100 000 | 8.6 | Europe | Value and class |
| Point prevalence | 1-9 / 100 000 | — | Europe | Class only |
| Prevalence at birth | 1-9 / 100 000 | 9.8 | Austria | Value and class |
| Prevalence at birth | 1-5 / 10 000 | 14.6 | Belgium | Value and class |
| Prevalence at birth | 1-5 / 10 000 | 21.3 | Denmark | Value and class |
| Prevalence at birth | 1-5 / 10 000 | 15.7 | France | Value and class |
| Prevalence at birth | 1-9 / 100 000 | 5.9 | Germany | Value and class |
| Prevalence at birth | 1-5 / 10 000 | 10 | Hungary | Value and class |
| Prevalence at birth | 1-9 / 100 000 | 7.2 | Ireland | Value and class |
| Prevalence at birth | 1-9 / 100 000 | 5.7 | Italy | Value and class |
| Prevalence at birth | 1-5 / 10 000 | 11.7 | Netherlands | Value and class |
| Prevalence at birth | 1-9 / 100 000 | 4.9 | Norway | Value and class |
| Prevalence at birth | 1-9 / 100 000 | 2.2 | Poland | Value and class |
| Prevalence at birth | 1-9 / 100 000 | 6.3 | Spain | Value and class |
| Prevalence at birth | 1-5 / 10 000 | 12.6 | Switzerland | Value and class |
| Prevalence at birth | 1-9 / 100 000 | 8.9 | United Kingdom | Value and class |
| Prevalence at birth | 1-9 / 100 000 | 3.2 | Ukraine | Value and class |
Лекарства и терапия
Источник: Open Targets Platform (в реальном времени)
Клинические исследования
Источник: ClinicalTrials.gov (в реальном времени)