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Ring chromosome 22 syndrome

ORPHA:1446Malformation syndromeInfancy, Neonatal

Фенотипы (33)

Частый (30–79%)30
HP:0000027Azoospermia
HP:0000252Microcephaly
HP:0000268Dolichocephaly
HP:0000276Long face
HP:0000286Epicanthus
HP:0000293Full cheeks
HP:0000307Pointed chin
HP:0000400Macrotia
HP:0000414Bulbous nose
HP:0000574Thick eyebrow
HP:0000719Inappropriate behavior
HP:0000729Autistic behavior
HP:0000750Delayed speech and language development
HP:0000969Edema
HP:0001004Lymphedema
HP:0001067Neurofibromas
HP:0001176Large hands
HP:0001250Seizure
HP:0001263Global developmental delay
HP:0001290Generalized hypotonia
HP:0001510Growth delay
HP:0002066Gait ataxia
HP:0002376Developmental regression
HP:00046912-3 toe syndactyly
HP:0007328Impaired pain sensation
HP:0010808Protruding tongue
HP:0011800Midface retrusion
HP:0012471Thick vermilion border
HP:0012810Wide nasal base
HP:0100797Toenail dysplasia
Периодический (5–29%)3
HP:0001274Agenesis of corpus callosum
HP:0001331Absent septum pellucidum
HP:0002202Pleural effusion

Эпидемиология (2)

Cases/families
Worldwide
Point prevalence
<1 / 1 000 000
Worldwide

Лекарства и терапия

Источник: Open Targets Platform (в реальном времени)

Клинические исследования

Источник: ClinicalTrials.gov (в реальном времени)

Внешние ресурсы