Dermatitis herpetiformis
ORPHA:1656DiseaseNot applicableAll ages
Фенотипы (HPO)26
Очень частый (80–99%)11
HP:0000989Pruritus
HP:0001025Urticaria
HP:0001935Microcytic anemia
HP:0002024Malabsorption
HP:0002757Recurrent fractures
HP:0002960Autoimmunity
HP:0008066Abnormal blistering of the skin
HP:0010783Erythema
HP:0012538Gluten intolerance
HP:0012733Macule
HP:0200037Skin vesicle
Частый (30–79%)7
HP:0000964Eczematoid dermatitis
HP:0033565Anti-epidermal transglutaminase antibody positivity
HP:0033637Anti-endomysial antibody positivity
HP:4000026Anti-transglutaminase 6 antibody
HP:4000029Antigliadin antibody positivity
HP:4000030Anti-reticulin antibody positivity
HP:4000031Anti-type VII collagen antibody
Периодический (5–29%)6
HP:0000684Delayed eruption of teeth
HP:0000820Abnormality of the thyroid gland
HP:0000969Edema
HP:0002653Bone pain
HP:0009722Dental enamel pits
HP:0100725Lichenification
Очень редкий (1–4%)2
HP:0000707Abnormality of the nervous system
HP:0031446Erosion of oral mucosa
Эпидемиология11
| Тип оценки | Класс распространённости | Среднее (на 100к) | Регион | Квалификация |
|---|---|---|---|---|
| Point prevalence | 1-5 / 10 000 | 27 | Europe | Value and class |
| Annual incidence | 1-9 / 1 000 000 | 0.9 | Italy | Value and class |
| Annual incidence | 1-9 / 100 000 | 1.5 | Ireland | Value and class |
| Point prevalence | 1-5 / 10 000 | 17.6 | Ireland | Value and class |
| Annual incidence | 1-9 / 100 000 | 1.1 | Sweden | Value and class |
| Point prevalence | 1-5 / 10 000 | 21 | Sweden | Value and class |
| Annual incidence | 1-9 / 1 000 000 | 0.98 | United States | Value and class |
| Point prevalence | 1-5 / 10 000 | 11.2 | United States | Value and class |
| Annual incidence | 1-9 / 100 000 | 3.5 | Finland | Value and class |
| Point prevalence | 6-9 / 10 000 | 75.3 | Finland | Value and class |
| Point prevalence | 1-5 / 10 000 | 11.5 | United Kingdom | Value and class |
Лекарства и терапия
Источник: Open Targets Platform (в реальном времени)
Клинические исследования
Источник: ClinicalTrials.gov (в реальном времени)