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Multiple epiphyseal dysplasia, Lowry type

ORPHA:166016DiseaseNeonatal

Фенотипы (20)

Очень частый (80–99%)18
HP:0000316Hypertelorism
HP:0000347Micrognathia
HP:0000455Broad nasal tip
HP:0000582Upslanted palpebral fissure
HP:0000766Abnormal sternum morphology
HP:0001156Brachydactyly
HP:0002650Scoliosis
HP:0002656Epiphyseal dysplasia
HP:0002663Delayed epiphyseal ossification
HP:0002857Genu valgum
HP:0003038Fibular hypoplasia
HP:0003071Flattened epiphysis
HP:0003083Dislocated radial head
HP:0004322Short stature
HP:0008905Rhizomelia
HP:0010585Small epiphyses
HP:0100168Fragmented epiphyses
HP:0410005Cleft hard palate
Частый (30–79%)2
HP:0006380Knee flexion contracture
HP:0006471Fixed elbow flexion

Эпидемиология (2)

Cases/families
Worldwide
Point prevalence
<1 / 1 000 000
Worldwide

Лекарства и терапия

Источник: Open Targets Platform (в реальном времени)

Клинические исследования

Источник: ClinicalTrials.gov (в реальном времени)

Внешние ресурсы