Polyembryoma
ORPHA:180229DiseaseNot applicableAdolescent, Adult
Фенотипы (HPO)19
Частый (30–79%)3
HP:0010785Gonadal neoplasm
HP:0030061Neuroectodermal neoplasm
HP:0030338Abnormal circulating gonadotropin level
Периодический (5–29%)8
HP:0002027Abdominal pain
HP:0002585Abnormality of the peritoneum
HP:0005107Abnormal sacrum morphology
HP:0006254Elevated alpha-fetoprotein
HP:0012288Neoplasm of head and neck
HP:0031500Abdominal mass
HP:0040231Abnormal onset of bleeding
HP:0045026Abnormality of the mediastinum
Очень редкий (1–4%)8
HP:0000053Macroorchidism
HP:0000818Abnormality of the endocrine system
HP:0000858Irregular menstruation
HP:0001945Fever
HP:0003144Increased serum serotonin
HP:0003270Abdominal distention
HP:0008236Isosexual precocious puberty
HP:0030088Increased serum testosterone level
Эпидемиология1
| Тип оценки | Класс распространённости | Среднее (на 100к) | Регион | Квалификация |
|---|---|---|---|---|
| Annual incidence | <1 / 1 000 000 | — | Europe | Class only |
Лекарства и терапия
Источник: Open Targets Platform (в реальном времени)
Клинические исследования
Источник: ClinicalTrials.gov (в реальном времени)