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Leukomelanoderma-infantilism-intellectual disability-hypodontia-hypotrichosis syndrome

ORPHA:1816Malformation syndromeAutosomal recessiveNeonatal

Фенотипы (16)

Очень частый (80–99%)16
HP:0000047Hypospadias
HP:0000144Decreased fertility
HP:0000457Depressed nasal ridge
HP:0000534Abnormal eyebrow morphology
HP:0000668Hypodontia
HP:0000684Delayed eruption of teeth
HP:0000787Nephrolithiasis
HP:0000823Delayed puberty
HP:0000982Palmoplantar keratoderma
HP:0001249Intellectual disability
HP:0002230Generalized hirsutism
HP:0004322Short stature
HP:0007400Irregular hyperpigmentation
HP:0007513Generalized hypopigmentation
HP:0008736Hypoplasia of penis
HP:0009721Shagreen patch

Эпидемиология (2)

Cases/families
Worldwide
Point prevalence
<1 / 1 000 000
Worldwide

Лекарства и терапия

Источник: Open Targets Platform (в реальном времени)

Клинические исследования

Источник: ClinicalTrials.gov (в реальном времени)

Внешние ресурсы