Fetal valproate spectrum disorder
ORPHA:1906Malformation syndromeNot applicableAntenatal, Childhood, Infancy, Neonatal
Фенотипы (HPO)8
Очень частый (80–99%)8
HP:0000160Narrow mouth
HP:0000233Thin vermilion border
HP:0000286Epicanthus
HP:0000343Long philtrum
HP:0000457Depressed nasal ridge
HP:0001539Omphalocele
HP:0002714Downturned corners of mouth
HP:0003196Short nose
Эпидемиология8
| Тип оценки | Класс распространённости | Среднее (на 100к) | Регион | Квалификация |
|---|---|---|---|---|
| Point prevalence | Unknown | — | Worldwide | Class only |
| Prevalence at birth | 1-9 / 100 000 | 1.02 | Europe | Value and class |
| Prevalence at birth | 1-5 / 10 000 | 11.7 | Reunion | Value and class |
| Prevalence at birth | 1-9 / 1 000 000 | 0.5 | Belgium | Value and class |
| Prevalence at birth | 1-9 / 100 000 | 1.7 | Netherlands | Value and class |
| Prevalence at birth | 1-9 / 100 000 | 1.3 | Switzerland | Value and class |
| Prevalence at birth | 1-9 / 100 000 | 1.2 | Germany | Value and class |
| Prevalence at birth | 1-9 / 100 000 | 1.3 | Ireland | Value and class |
Лекарства и терапия
Источник: Open Targets Platform (в реальном времени)
Клинические исследования
Источник: ClinicalTrials.gov (в реальном времени)