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Vitamin K antagonist embryofetopathy

ORPHA:1914Malformation syndromeNot applicableAntenatal, Neonatal

Фенотипы (26)

Очень частый (80–99%)5
HP:0000463Anteverted nares
HP:0003196Short nose
HP:0005280Depressed nasal bridge
HP:0008420Punctate vertebral calcifications
HP:0010655Epiphyseal stippling
Частый (30–79%)6
HP:0000470Short neck
HP:0001156Brachydactyly
HP:0001249Intellectual disability
HP:0001511Intrauterine growth retardation
HP:0002093Respiratory insufficiency
HP:0009882Short distal phalanx of finger
Периодический (5–29%)15
HP:0000158Macroglossia
HP:0000238Hydrocephalus
HP:0000316Hypertelorism
HP:0000365Hearing impairment
HP:0000453Choanal atresia
HP:0000505Visual impairment
HP:0000518Cataract
HP:0000520Proptosis
HP:0000648Optic atrophy
HP:0001250Seizure
HP:0001252Hypotonia
HP:0002475Myelomeningocele
HP:0008056Aplasia/Hypoplasia affecting the eye
HP:0008551Microtia
HP:0030680Abnormal cardiovascular system morphology

Эпидемиология (1)

Point prevalence
Unknown
Worldwide

Лекарства и терапия

Источник: Open Targets Platform (в реальном времени)

Клинические исследования

Источник: ClinicalTrials.gov (в реальном времени)

Внешние ресурсы