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Flynn-Aird syndrome

ORPHA:2047DiseaseAutosomal dominantChildhood

Фенотипы (30)

Очень частый (80–99%)3
HP:0000408Progressive sensorineural hearing impairment
HP:0000545Myopia
HP:0004334Dermal atrophy
Частый (30–79%)19
HP:0000510Rod-cone dystrophy
HP:0000518Cataract
HP:0000726Dementia
HP:0001250Seizure
HP:0001251Ataxia
HP:0001387Joint stiffness
HP:0001596Alopecia
HP:0002353EEG abnormality
HP:0002376Developmental regression
HP:0002381Aphasia
HP:0002621Atherosclerosis
HP:0002650Scoliosis
HP:0002808Kyphosis
HP:0003202Skeletal muscle atrophy
HP:0004326Cachexia
HP:0007328Impaired pain sensation
HP:0009830Peripheral neuropathy
HP:0012062Bone cyst
HP:0200042Skin ulcer
Периодический (5–29%)8
HP:0000505Visual impairment
HP:0000670Carious teeth
HP:0000820Abnormality of the thyroid gland
HP:0002120Cerebral cortical atrophy
HP:0002514Cerebral calcification
HP:0005978Type II diabetes mellitus
HP:0008207Primary adrenal insufficiency
HP:0100022Abnormality of movement

Эпидемиология (2)

Cases/families
Worldwide
Point prevalence
<1 / 1 000 000
Worldwide

Лекарства и терапия

Источник: Open Targets Platform (в реальном времени)

Клинические исследования

Источник: ClinicalTrials.gov (в реальном времени)

Внешние ресурсы