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Maternal uniparental disomy of chromosome 1 syndrome

ORPHA:251009Malformation syndromeNot applicable, UnknownInfancy, Neonatal

Фенотипы (29)

Частый (30–79%)29
HP:0000319Smooth philtrum
HP:0000365Hearing impairment
HP:0000518Cataract
HP:0000639Nystagmus
HP:0000717Autism
HP:0000954Single transverse palmar crease
HP:0001250Seizure
HP:0001251Ataxia
HP:0001319Neonatal hypotonia
HP:0001476Delayed closure of the anterior fontanelle
HP:0001508Failure to thrive
HP:0001510Growth delay
HP:0001876Pancytopenia
HP:0001883Talipes
HP:0002020Gastroesophageal reflux
HP:0002119Ventriculomegaly
HP:0002191Progressive spasticity
HP:0002240Hepatomegaly
HP:0002714Downturned corners of mouth
HP:0002719Recurrent infections
HP:0002813Abnormality of limb bone morphology
HP:0003139Panhypogammaglobulinemia
HP:0004322Short stature
HP:0007272Progressive psychomotor deterioration
HP:0008066Abnormal blistering of the skin
HP:0009909Uplifted earlobe
HP:0010655Epiphyseal stippling
HP:0011968Feeding difficulties
HP:0100651Type I diabetes mellitus

Эпидемиология (1)

Point prevalence
Unknown
Worldwide

Лекарства и терапия

Источник: Open Targets Platform (в реальном времени)

Клинические исследования

Источник: ClinicalTrials.gov (в реальном времени)

Внешние ресурсы