Idiopathic pulmonary arterial hypertension

ORPHA:275766Etiological subtypeNot applicableAll ages

Фенотипы (HPO)18

Облигатный (100%)1

HP:0002094Dyspnea

Очень частый (80–99%)5

HP:0001667Right ventricular hypertrophy

HP:0002092Pulmonary arterial hypertension

HP:0004890Elevated pulmonary artery pressure

HP:0005317Increased pulmonary vascular resistance

HP:3000042Abnormal jugular vein morphology

Частый (30–79%)7

HP:0001279Syncope

HP:0001635Congestive heart failure

HP:0001785Ankle swelling

HP:0005180Tricuspid regurgitation

HP:0012098Edema of the dorsum of feet

HP:0030148Heart murmur

HP:0100749Chest pain

Периодический (5–29%)3

HP:0001962Palpitations

HP:0002105Hemoptysis

HP:0010741Pedal edema

Исключён (0%)2

HP:0003549Abnormality of connective tissue

HP:0004870Chronic hemolytic anemia

Тип оценки	Класс распространённости	Среднее (на 100к)	Регион	Квалификация
Point prevalence	1-9 / 1 000 000	—	Worldwide	Class only
Point prevalence	1-9 / 1 000 000	0.59	France	Value and class
Annual incidence	1-9 / 1 000 000	0.1	France	Value and class
Point prevalence	1-9 / 1 000 000	0.56	Spain	Value and class
Annual incidence	1-9 / 1 000 000	0.12	Spain	Value and class
Point prevalence	1-9 / 100 000	1.4	Czech Republic	Value and class
Annual incidence	1-9 / 1 000 000	0.62	Czech Republic	Value and class
Point prevalence	1-9 / 1 000 000	0.86	Switzerland	Value and class
Annual incidence	1-9 / 1 000 000	0.12	Switzerland	Value and class
Annual incidence	1-9 / 1 000 000	0.25	United Kingdom	Value and class
Point prevalence	1-9 / 100 000	1.7	United Kingdom	Value and class
Annual incidence	1-9 / 1 000 000	0.11	United States	Value and class
Annual incidence	1-9 / 1 000 000	0.17	Belgium	Value and class
Annual incidence	1-9 / 1 000 000	0.14	Israel	Value and class
Point prevalence	1-9 / 1 000 000	0.8	Israel	Value and class
Point prevalence	1-9 / 100 000	1.1	Europe	Value and class

Источник: Open Targets Platform (в реальном времени)

Источник: ClinicalTrials.gov (в реальном времени)