Cyanide-induced parkinsonism-dystonia
ORPHA:306692DiseaseAll ages
Фенотипы (HPO)20
Частый (30–79%)20
HP:0000298Mask-like facies
HP:0000741Apathy
HP:0001260Dysarthria
HP:0001300Parkinsonism
HP:0002063Rigidity
HP:0002067Bradykinesia
HP:0002120Cerebral cortical atrophy
HP:0002167Abnormality of speech or vocalization
HP:0002172Postural instability
HP:0002322Resting tremor
HP:0002362Shuffling gait
HP:0002425Anarthria
HP:0002527Falls
HP:0002987Elbow flexion contracture
HP:0004673Decreased facial expression
HP:0007034Generalized hyperreflexia
HP:0007311Short stepped shuffling gait
HP:0007975Hypometric horizontal saccades
HP:0011121Abnormal skin morphology
HP:0012157Subcortical cerebral atrophy
Лекарства и терапия
Источник: Open Targets Platform (в реальном времени)
Клинические исследования
Источник: ClinicalTrials.gov (в реальном времени)