Rheumatic fever
ORPHA:3099DiseaseNot applicableChildhood
Фенотипы (HPO)36
Очень частый (80–99%)5
HP:0001369Arthritis
HP:0001482Subcutaneous nodule
HP:0002017Nausea and vomiting
HP:0002039Anorexia
HP:0012733Macule
Частый (30–79%)14
HP:0000246Sinusitis
HP:0000980Pallor
HP:0001633Abnormal mitral valve morphology
HP:0001646Abnormal aortic valve morphology
HP:0001945Fever
HP:0002027Abdominal pain
HP:0002072Chorea
HP:0002829Arthralgia
HP:0011675Arrhythmia
HP:0012378Fatigue
HP:0012819Myocarditis
HP:0100584Endocarditis
HP:0100749Chest pain
HP:0100776Recurrent pharyngitis
Периодический (5–29%)17
HP:0000100Nephrotic syndrome
HP:0000421Epistaxis
HP:0000708Atypical behavior
HP:0001288Gait disturbance
HP:0001654Abnormal heart valve morphology
HP:0001701Pericarditis
HP:0002019Constipation
HP:0002076Migraine
HP:0002093Respiratory insufficiency
HP:0002103Abnormality of the pleura
HP:0002167Abnormality of speech or vocalization
HP:0002380Fasciculations
HP:0010318Aplasia/Hypoplasia of the abdominal wall musculature
HP:0010522Dyslexia
HP:0010526Dysgraphia
HP:0010783Erythema
HP:0100248Hemiballismus
Эпидемиология9
| Тип оценки | Класс распространённости | Среднее (на 100к) | Регион | Квалификация |
|---|---|---|---|---|
| Annual incidence | 1-9 / 100 000 | 5 | Europe | Value and class |
| Annual incidence | 1-5 / 10 000 | 12.5 | Canada | Value and class |
| Annual incidence | 1-5 / 10 000 | 12.5 | Spain | Value and class |
| Annual incidence | >1 / 1000 | 100 | Australia | Value and class |
| Annual incidence | 1-5 / 10 000 | 30 | India | Value and class |
| Annual incidence | >1 / 1000 | 100 | Mexico | Value and class |
| Annual incidence | 1-9 / 100 000 | 5 | Latin America | Value and class |
| Annual incidence | 1-9 / 100 000 | 7.6 | New Zealand | Value and class |
| Point prevalence | Unknown | — | Worldwide | Class only |
Лекарства и терапия
Источник: Open Targets Platform (в реальном времени)
Клинические исследования
Источник: ClinicalTrials.gov (в реальном времени)