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Deafness-genital anomalies-metacarpal and metatarsal synostosis syndrome

ORPHA:3224Malformation syndromeInfancy, Neonatal

Фенотипы (28)

Очень частый (80–99%)16
HP:0000047Hypospadias
HP:0000324Facial asymmetry
HP:0000358Posteriorly rotated ears
HP:0000369Low-set ears
HP:0000407Sensorineural hearing impairment
HP:0000411Protruding ear
HP:0001249Intellectual disability
HP:0001321Cerebellar hypoplasia
HP:0001761Pes cavus
HP:0002119Ventriculomegaly
HP:0002120Cerebral cortical atrophy
HP:0002334Abnormality of the cerebellar vermis
HP:0005105Abnormal nasal morphology
HP:0005916Abnormal metacarpal morphology
HP:0007477Abnormal dermatoglyphics
HP:0011220Prominent forehead
Частый (30–79%)12
HP:0000164Abnormality of the dentition
HP:0000286Epicanthus
HP:0000316Hypertelorism
HP:0001273Abnormal corpus callosum morphology
HP:0001596Alopecia
HP:0001770Toe syndactyly
HP:0001956Truncal obesity
HP:0002167Abnormality of speech or vocalization
HP:0002558Supernumerary nipple
HP:0003468Abnormal vertebral morphology
HP:0006101Finger syndactyly
HP:0010109Short hallux

Эпидемиология (2)

Cases/families
Worldwide
Point prevalence
<1 / 1 000 000
Worldwide

Лекарства и терапия

Источник: Open Targets Platform (в реальном времени)

Клинические исследования

Источник: ClinicalTrials.gov (в реальном времени)

Внешние ресурсы