← Назад

Radioulnar synostosis-developmental delay-hypotonia syndrome

ORPHA:3270Malformation syndromeUnknownNeonatal

Фенотипы (20)

Очень частый (80–99%)17
HP:0000174Abnormal palate morphology
HP:0000256Macrocephaly
HP:0000268Dolichocephaly
HP:0000275Narrow face
HP:0000364Hearing abnormality
HP:0000411Protruding ear
HP:0000426Prominent nasal bridge
HP:0000448Prominent nose
HP:0000486Strabismus
HP:0000767Pectus excavatum
HP:0001252Hypotonia
HP:0001263Global developmental delay
HP:0001288Gait disturbance
HP:0002167Abnormality of speech or vocalization
HP:0002974Radioulnar synostosis
HP:0003011Abnormality of the musculature
HP:0007477Abnormal dermatoglyphics
Частый (30–79%)3
HP:0000003Multicystic kidney dysplasia
HP:0000164Abnormality of the dentition
HP:0000670Carious teeth

Эпидемиология (2)

Cases/families
Worldwide
Point prevalence
<1 / 1 000 000
Worldwide

Лекарства и терапия

Источник: Open Targets Platform (в реальном времени)

Клинические исследования

Источник: ClinicalTrials.gov (в реальном времени)

Внешние ресурсы