African trypanosomiasis
ORPHA:3385DiseaseNot applicableAll ages
Фенотипы (HPO)87
Очень частый (80–99%)6
HP:0000707Abnormality of the nervous system
HP:0001262Excessive daytime somnolence
HP:0002360Sleep abnormality
HP:0006979Sleep-wake cycle disturbance
HP:0030050Narcolepsy
HP:0032323Periodic fever
Частый (30–79%)19
HP:0000741Apathy
HP:0000989Pruritus
HP:0001324Muscle weakness
HP:0001433Hepatosplenomegaly
HP:0001744Splenomegaly
HP:0001824Weight loss
HP:0002240Hepatomegaly
HP:0002315Headache
HP:0002494Abnormal rapid eye movement sleep
HP:0002500Abnormal cerebral white matter morphology
HP:0002716Lymphadenopathy
HP:0003115Abnormal EKG
HP:0011442Abnormality of central motor function
HP:0012378Fatigue
HP:0012751Abnormal basal ganglia MRI signal intensity
HP:0025145Rigors
HP:0100785Insomnia
HP:0410263Brain imaging abnormality
HP:0001288Gait disturbance
Периодический (5–29%)48
HP:0000020Urinary incontinence
HP:0000083Renal insufficiency
HP:0000140Abnormality of the menstrual cycle
HP:0000491Keratitis
HP:0000509Conjunctivitis
HP:0000651Diplopia
HP:0000708Atypical behavior
HP:0000718Aggressive behavior
HP:0000737Irritability
HP:0000739Anxiety
HP:0000771Gynecomastia
HP:0000789Infertility
HP:0000802Impotence
HP:0000818Abnormality of the endocrine system
HP:0000847Abnormality of renin-angiotensin system
HP:0000952Jaundice
HP:0001101Iritis
HP:0001266Choreoathetosis
HP:0001269Hemiparesis
HP:0001288Gait disturbance
HP:0001337Tremor
HP:0001345Psychotic mentation
HP:0001596Alopecia
HP:0001709Third degree atrioventricular block
HP:0002013Vomiting
HP:0002014Diarrhea
HP:0002018Nausea
HP:0002119Ventriculomegaly
HP:0002167Abnormality of speech or vocalization
HP:0002304Akinesia
HP:0002380Fasciculations
HP:0002476Primitive reflex
HP:0002829Arthralgia
HP:0003401Paresthesia
HP:0003470Paralysis
HP:0003474Somatic sensory dysfunction
HP:0004305Involuntary movements
HP:0004372Reduced consciousness/confusion
HP:0005521Disseminated intravascular coagulation
HP:0006824Cranial nerve paralysis
HP:0007178Motor polyneuropathy
HP:0010831Impaired proprioception
HP:0011706Second degree atrioventricular block
HP:0011731Abnormality of circulating cortisol level
HP:0032367Abnormal growth hormone level
HP:0040086Abnormal prolactin level
HP:0100653Optic neuritis
HP:0100660Dyskinesia
Очень редкий (1–4%)14
HP:0000738Hallucinations
HP:0001085Papilledema
HP:0001250Seizure
HP:0001259Coma
HP:0001622Premature birth
HP:0001635Congestive heart failure
HP:0001701Pericarditis
HP:0002196Myelopathy
HP:0005268Spontaneous abortion
HP:0011675Arrhythmia
HP:0012486Myelitis
HP:0012819Myocarditis
HP:0025475Erythematous macule
HP:0031258Delirium
Эпидемиология1
| Тип оценки | Класс распространённости | Среднее (на 100к) | Регион | Квалификация |
|---|---|---|---|---|
| Point prevalence | Unknown | — | Worldwide | Class only |
Лекарства и терапия
Источник: Open Targets Platform (в реальном времени)
Клинические исследования
Источник: ClinicalTrials.gov (в реальном времени)