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Epidermal nevus syndrome

ORPHA:35125DiseaseNot applicableInfancy, Neonatal

Фенотипы (26)

Очень частый (80–99%)1
HP:0003764Nevus
Частый (30–79%)7
HP:0000953Hyperpigmentation of the skin
HP:0001010Hypopigmentation of the skin
HP:0002176Spinal cord compression
HP:0003416Spinal canal stenosis
HP:0006827Atrophy of the spinal cord
HP:0007199Progressive spastic paraparesis
HP:0012531Pain
Периодический (5–29%)12
HP:0000483Astigmatism
HP:0000505Visual impairment
HP:0000750Delayed speech and language development
HP:0001263Global developmental delay
HP:0001276Hypertonia
HP:0001284Areflexia
HP:0002944Thoracolumbar scoliosis
HP:0003487Babinski sign
HP:0009077Weakness of long finger extensor muscles
HP:0010302Spinal cord tumor
HP:0012032Lipoma
HP:0012443Abnormality of brain morphology
Очень редкий (1–4%)6
HP:0000113Polycystic kidney dysplasia
HP:0000938Osteopenia
HP:0001999Abnormal facial shape
HP:0002859Rhabdomyosarcoma
HP:0004942Aortic aneurysm
HP:0100512Low levels of vitamin D

Эпидемиология (2)

Cases/families
Worldwide
Point prevalence
Unknown
Worldwide

Лекарства и терапия

Источник: Open Targets Platform (в реальном времени)

Клинические исследования

Источник: ClinicalTrials.gov (в реальном времени)

Внешние ресурсы