Graft versus host disease
ORPHA:39812DiseaseNot applicableAll ages
Фенотипы (HPO)41
Очень частый (80–99%)1
HP:0011123Inflammatory abnormality of the skin
Частый (30–79%)8
HP:0000155Oral ulcer
HP:0002014Diarrhea
HP:0002719Recurrent infections
HP:0002910Elevated circulating hepatic transaminase concentration
HP:0010280Stomatitis
HP:0040186Maculopapular exanthema
HP:0200041Skin erosion
HP:0200123Chronic hepatitis
Периодический (5–29%)25
HP:0000737Irritability
HP:0000952Jaundice
HP:0001369Arthritis
HP:0001433Hepatosplenomegaly
HP:0001649Tachycardia
HP:0002013Vomiting
HP:0002018Nausea
HP:0002027Abdominal pain
HP:0002090Pneumonia
HP:0002113Pulmonary infiltrates
HP:0002904Hyperbilirubinemia
HP:0002996Limited elbow movement
HP:0003155Elevated circulating alkaline phosphatase concentration
HP:0003202Skeletal muscle atrophy
HP:0004386Gastrointestinal inflammation
HP:0006467Limited shoulder movement
HP:0012156Hemophagocytosis
HP:0031123Recurrent gastroenteritis
HP:0031359Cutaneous sclerotic plaque
HP:0031452Lichenoid skin lesion
HP:0040189Scaling skin
HP:0100533Inflammatory abnormality of the eye
HP:0100537Fasciitis
HP:0100614Myositis
HP:0200119Acute hepatitis
Очень редкий (1–4%)7
HP:0000211Trismus
HP:0000633Decreased lacrimation
HP:0001508Failure to thrive
HP:0002716Lymphadenopathy
HP:0005198Stiff interphalangeal joints
HP:0005679Dupuytren contracture
HP:0009125Lipodystrophy
Эпидемиология1
| Тип оценки | Класс распространённости | Среднее (на 100к) | Регион | Квалификация |
|---|---|---|---|---|
| Point prevalence | 1-9 / 100 000 | 5 | Europe | Value and class |
Лекарства и терапия
Источник: Open Targets Platform (в реальном времени)
Клинические исследования
Источник: ClinicalTrials.gov (в реальном времени)