Serotonin syndrome
ORPHA:43116DiseaseNot applicableAll ages
Фенотипы (HPO)34
Очень частый (80–99%)1
HP:0002270Abnormality of the autonomic nervous system
Частый (30–79%)11
HP:0000711Restlessness
HP:0000737Irritability
HP:0000739Anxiety
HP:0001268Mental deterioration
HP:0001289Confusion
HP:0001336Myoclonus
HP:0001337Tremor
HP:0001649Tachycardia
HP:0002014Diarrhea
HP:0002018Nausea
HP:0100785Insomnia
Периодический (5–29%)11
HP:0000570Abnormal saccadic eye movements
HP:0000713Agitation
HP:0000822Hypertension
HP:0000975Hyperhidrosis
HP:0001250Seizure
HP:0001347Hyperreflexia
HP:0002169Clonus
HP:0002789Tachypnea
HP:0003128Lactic acidosis
HP:0011499Mydriasis
HP:0032044Decreased vigilance
Очень редкий (1–4%)11
HP:0000738Hallucinations
HP:0001259Coma
HP:0001276Hypertonia
HP:0001399Hepatic failure
HP:0001919Acute kidney injury
HP:0001945Fever
HP:0002063Rigidity
HP:0002615Hypotension
HP:0003201Rhabdomyolysis
HP:0005521Disseminated intravascular coagulation
HP:0031258Delirium
Эпидемиология1
| Тип оценки | Класс распространённости | Среднее (на 100к) | Регион | Квалификация |
|---|---|---|---|---|
| Point prevalence | Unknown | — | Worldwide | Class only |
Лекарства и терапия
Источник: Open Targets Platform (в реальном времени)
Клинические исследования
Источник: ClinicalTrials.gov (в реальном времени)