Kikuchi-Fujimoto disease
ORPHA:50918DiseaseAdolescent, Adult, Childhood, Infancy
Фенотипы (HPO)50
Очень частый (80–99%)1
HP:0025289Cervical lymphadenopathy
Частый (30–79%)21
HP:0000155Oral ulcer
HP:0000988Skin rash
HP:0000989Pruritus
HP:0000992Cutaneous photosensitivity
HP:0001596Alopecia
HP:0001824Weight loss
HP:0001882Leukopenia
HP:0002039Anorexia
HP:0002633Vasculitis
HP:0002716Lymphadenopathy
HP:0002733Abnormality of the lymph nodes
HP:0010783Erythema
HP:0011134Low-grade fever
HP:0012378Fatigue
HP:0025143Chills
HP:0025300Malar rash
HP:0025435Increased circulating lactate dehydrogenase concentration
HP:0030166Night sweats
HP:0100540Palpebral edema
HP:0200029Vasculitis in the skin
HP:0200036Skin nodule
Периодический (5–29%)22
HP:0000464Abnormality of the neck
HP:0001287Meningitis
HP:0001744Splenomegaly
HP:0001873Thrombocytopenia
HP:0001875Decreased total neutrophil count
HP:0001903Anemia
HP:0002829Arthralgia
HP:0002910Elevated circulating hepatic transaminase concentration
HP:0003326Myalgia
HP:0003493Antinuclear antibody positivity
HP:0003565Elevated erythrocyte sedimentation rate
HP:0006530Abnormal pulmonary interstitial morphology
HP:0008066Abnormal blistering of the skin
HP:0011024Abnormality of the gastrointestinal tract
HP:0011227Elevated circulating C-reactive protein concentration
HP:0011801Enlargement of parotid gland
HP:0012733Macule
HP:0025475Erythematous macule
HP:0100827Lymphocytosis
HP:0200034Papule
HP:0200035Skin plaque
HP:0200041Skin erosion
Очень редкий (1–4%)6
HP:0001251Ataxia
HP:0002202Pleural effusion
HP:0002240Hepatomegaly
HP:0008940Generalized lymphadenopathy
HP:0012819Myocarditis
HP:0200039Pustule
Эпидемиология3
| Тип оценки | Класс распространённости | Среднее (на 100к) | Регион | Квалификация |
|---|---|---|---|---|
| Point prevalence | Unknown | — | Worldwide | Class only |
| Cases/families | — | 1052 | Worldwide | Case(s) |
| Annual incidence | 1-9 / 1 000 000 | 0.278 | Martinique | Value and class |
Лекарства и терапия
Источник: Open Targets Platform (в реальном времени)
Клинические исследования
Источник: ClinicalTrials.gov (в реальном времени)