Toxic epidermal necrolysis
ORPHA:537Clinical subtypeNot applicableAll ages
Фенотипы (HPO)39
Очень частый (80–99%)11
HP:0001824Weight loss
HP:0001873Thrombocytopenia
HP:0001875Decreased total neutrophil count
HP:0001959Polydipsia
HP:0002015Dysphagia
HP:0008066Abnormal blistering of the skin
HP:0010783Erythema
HP:0012378Fatigue
HP:0012733Macule
HP:0100792Acantholysis
HP:0100806Sepsis
Частый (30–79%)8
HP:0001903Anemia
HP:0002024Malabsorption
HP:0002027Abdominal pain
HP:0002205Recurrent respiratory infections
HP:0002910Elevated circulating hepatic transaminase concentration
HP:0003781Excessive salivation
HP:0012735Cough
HP:0100518Dysuria
Периодический (5–29%)20
HP:0000083Renal insufficiency
HP:0000142Abnormality of the vagina
HP:0000509Conjunctivitis
HP:0000572Visual loss
HP:0000613Photophobia
HP:0000621Entropion
HP:0000795Abnormality of the urethra
HP:0001637Abnormal myocardium morphology
HP:0001645Sudden cardiac death
HP:0001733Pancreatitis
HP:0002017Nausea and vomiting
HP:0002091Restrictive ventilatory defect
HP:0002098Respiratory distress
HP:0002103Abnormality of the pleura
HP:0002239Gastrointestinal hemorrhage
HP:0002575Tracheoesophageal fistula
HP:0006554Acute hepatic failure
HP:0031368Intestinal perforation
HP:0200020Corneal erosion
HP:0200042Skin ulcer
Эпидемиология1
| Тип оценки | Класс распространённости | Среднее (на 100к) | Регион | Квалификация |
|---|---|---|---|---|
| Point prevalence | Unknown | — | Worldwide | Class only |
Лекарства и терапия
Источник: Open Targets Platform (в реальном времени)
Клинические исследования
Источник: ClinicalTrials.gov (в реальном времени)