Necrobiosis lipoidica
ORPHA:542592DiseaseAdolescent, Adult, Childhood, Elderly
Фенотипы (HPO)21
Очень частый (80–99%)2
HP:0011123Inflammatory abnormality of the skin
HP:0025528Annular cutaneous lesion
Частый (30–79%)13
HP:0000819Diabetes mellitus
HP:0001030Fragile skin
HP:0001075Atrophic scars
HP:0002814Abnormality of the lower limb
HP:0010783Erythema
HP:0011990Abnormality of neutrophil physiology
HP:0032217Indurated nodule
HP:0032252Granuloma
HP:0100585Telangiectasia of the skin
HP:0200034Papule
HP:0200035Skin plaque
HP:0200036Skin nodule
HP:0200042Skin ulcer
Периодический (5–29%)4
HP:0000271Abnormality of the face
HP:0001155Abnormality of the hand
HP:0001965Abnormality of the scalp
HP:0002973Abnormality of the forearm
Очень редкий (1–4%)2
HP:0000820Abnormality of the thyroid gland
HP:0002860Squamous cell carcinoma
Эпидемиология1
| Тип оценки | Класс распространённости | Среднее (на 100к) | Регион | Квалификация |
|---|---|---|---|---|
| Point prevalence | Unknown | — | Worldwide | Class only |
Лекарства и терапия
Источник: Open Targets Platform (в реальном времени)
Клинические исследования
Источник: ClinicalTrials.gov (в реальном времени)