Infection-related hemolytic uremic syndrome
ORPHA:544482DiseaseNot applicableAll ages
Фенотипы (HPO)52
Очень частый (80–99%)6
HP:0000980Pallor
HP:0001873Thrombocytopenia
HP:0001878Hemolytic anemia
HP:0001919Acute kidney injury
HP:0012378Fatigue
HP:0032169Severe infection
Частый (30–79%)12
HP:0000707Abnormality of the nervous system
HP:0001945Fever
HP:0001974Leukocytosis
HP:0002014Diarrhea
HP:0002027Abdominal pain
HP:0011037Decreased urine output
HP:0011115Abnormality of chemokine secretion
HP:0011116Abnormality of interferon secretion
HP:0011947Respiratory tract infection
HP:0030783Increased circulating interleukin 6 concentration
HP:0032155Abdominal cramps
HP:0100282Acute colitis
Периодический (5–29%)22
HP:0000822Hypertension
HP:0000969Edema
HP:0001287Meningitis
HP:0001733Pancreatitis
HP:0002013Vomiting
HP:0002018Nausea
HP:0002090Pneumonia
HP:0002094Dyspnea
HP:0002102Pleuritis
HP:0002153Hyperkalemia
HP:0002901Hypocalcemia
HP:0002902Hyponatremia
HP:0004372Reduced consciousness/confusion
HP:0005208Secretory diarrhea
HP:0012593Nephrotic range proteinuria
HP:0012819Myocarditis
HP:0025085Bloody diarrhea
HP:0031691Severe viral infection
HP:0031864Bacteremia
HP:0100519Anuria
HP:0100520Oliguria
HP:0100735Hypertensive crisis
Очень редкий (1–4%)12
HP:0000819Diabetes mellitus
HP:0001250Seizure
HP:0001259Coma
HP:0001269Hemiparesis
HP:0002576Intussusception
HP:0003095Septic arthritis
HP:0005244Gastrointestinal infarctions
HP:0007430Generalized edema
HP:0011919Pleural empyema
HP:0030049Brain abscess
HP:0031368Intestinal perforation
HP:0100704Cerebral visual impairment
Эпидемиология1
| Тип оценки | Класс распространённости | Среднее (на 100к) | Регион | Квалификация |
|---|---|---|---|---|
| Point prevalence | Unknown | — | Worldwide | Class only |
Лекарства и терапия
Источник: Open Targets Platform (в реальном времени)
Клинические исследования
Источник: ClinicalTrials.gov (в реальном времени)