Peripartum cardiomyopathy
ORPHA:563DiseaseUnknownAdult
Фенотипы (HPO)45
Частый (30–79%)16
HP:0000822Hypertension
HP:0001635Congestive heart failure
HP:0001644Dilated cardiomyopathy
HP:0001649Tachycardia
HP:0001712Left ventricular hypertrophy
HP:0001962Palpitations
HP:0002094Dyspnea
HP:0002875Exertional dyspnea
HP:0005135Abnormal T-wave
HP:0010741Pedal edema
HP:0011703Sinus tachycardia
HP:0012378Fatigue
HP:0012664Reduced left ventricular ejection fraction
HP:0012764Orthopnea
HP:0025169Left ventricular systolic dysfunction
HP:0030848Elevated jugular venous pressure
Периодический (5–29%)18
HP:0001653Mitral regurgitation
HP:0001708Right ventricular failure
HP:0001907Thromboembolism
HP:0002092Pulmonary arterial hypertension
HP:0004756Ventricular tachycardia
HP:0005120Abnormal cardiac atrium morphology
HP:0005133Right ventricular dilatation
HP:0006705Abnormal atrioventricular valve morphology
HP:0012398Peripheral edema
HP:0012763Paroxysmal dyspnea
HP:0012819Myocarditis
HP:0030148Heart murmur
HP:0030356Increased serum interferon-gamma level
HP:0030830Crackles
HP:0031295Left atrial enlargement
HP:0100602Preeclampsia
HP:0100603Toxemia of pregnancy
HP:0100749Chest pain
Очень редкий (1–4%)11
HP:0000819Diabetes mellitus
HP:0001513Obesity
HP:0001903Anemia
HP:0002027Abdominal pain
HP:0002099Asthma
HP:0002401Stroke-like episode
HP:0002878Respiratory failure
HP:0002926Abnormality of thyroid physiology
HP:0002960Autoimmunity
HP:0011713Left bundle branch block
HP:0030149Cardiogenic shock
Эпидемиология7
| Тип оценки | Класс распространённости | Среднее (на 100к) | Регион | Квалификация |
|---|---|---|---|---|
| Prevalence at birth | 1-5 / 10 000 | 30 | Worldwide | Value and class |
| Prevalence at birth | 1-5 / 10 000 | 36 | United States | Value and class |
| Prevalence at birth | 6-9 / 10 000 | 89 | Singapore | Value and class |
| Prevalence at birth | 1-9 / 100 000 | 5 | Japan | Value and class |
| Prevalence at birth | >1 / 1000 | 334 | Haiti | Value and class |
| Prevalence at birth | >1 / 1000 | 100 | South Africa | Value and class |
| Point prevalence | Unknown | — | Worldwide | Class only |
Лекарства и терапия
Источник: Open Targets Platform (в реальном времени)
Клинические исследования
Источник: ClinicalTrials.gov (в реальном времени)