Parenteral nutrition-associated cholestasis
ORPHA:567983Particular clinical situation in a disease or syndromeAll ages
Фенотипы (HPO)22
Частый (30–79%)16
HP:0000952Jaundice
HP:0001399Hepatic failure
HP:0001518Small for gestational age
HP:0001622Premature birth
HP:0001744Splenomegaly
HP:0002027Abdominal pain
HP:0002240Hepatomegaly
HP:0002910Elevated circulating hepatic transaminase concentration
HP:0003077Hyperlipidemia
HP:0003155Elevated circulating alkaline phosphatase concentration
HP:0004359Abnormal circulating fatty-acid concentration
HP:0006560Biliary hyperplasia
HP:0011113Abnormality of cytokine secretion
HP:0011473Villous atrophy
HP:0030948Elevated gamma-glutamyltransferase level
HP:0032245Abnormal metabolism
Периодический (5–29%)6
HP:0001081Cholelithiasis
HP:0001394Cirrhosis
HP:0001395Hepatic fibrosis
HP:0001397Hepatic steatosis
HP:0001409Portal hypertension
HP:0002908Conjugated hyperbilirubinemia
Эпидемиология1
| Тип оценки | Класс распространённости | Среднее (на 100к) | Регион | Квалификация |
|---|---|---|---|---|
| Point prevalence | Unknown | — | Worldwide | Class only |
Лекарства и терапия
Источник: Open Targets Platform (в реальном времени)
Клинические исследования
Источник: ClinicalTrials.gov (в реальном времени)