Recurrent respiratory papillomatosis
ORPHA:60032DiseaseNot applicableAdolescent, Adult, Childhood, Infancy
Фенотипы (HPO)23
Очень частый (80–99%)1
HP:0001609Hoarse voice
Частый (30–79%)3
HP:0001618Dysphonia
HP:0002098Respiratory distress
HP:0002778Abnormal trachea morphology
Периодический (5–29%)12
HP:0001508Failure to thrive
HP:0002015Dysphagia
HP:0002093Respiratory insufficiency
HP:0002094Dyspnea
HP:0002105Hemoptysis
HP:0002781Upper airway obstruction
HP:0002788Recurrent upper respiratory tract infections
HP:0002789Tachypnea
HP:0006532Recurrent pneumonia
HP:0010307Stridor
HP:0030828Wheezing
HP:0031246Nonproductive cough
Очень редкий (1–4%)7
HP:0001279Syncope
HP:0001945Fever
HP:0002088Abnormal lung morphology
HP:0002779Tracheomalacia
HP:0002860Squamous cell carcinoma
HP:0030842Choking episodes
HP:0100750Atelectasis
Эпидемиология6
| Тип оценки | Класс распространённости | Среднее (на 100к) | Регион | Квалификация |
|---|---|---|---|---|
| Point prevalence | 1-9 / 100 000 | 4 | Netherlands | Value and class |
| Annual incidence | 1-9 / 1 000 000 | 0.16 | Netherlands | Value and class |
| Annual incidence | 1-9 / 100 000 | 2.34 | United States | Value and class |
| Annual incidence | 1-9 / 1 000 000 | 0.76 | Denmark | Value and class |
| Point prevalence | 1-9 / 100 000 | 1.42 | United Kingdom | Value and class |
| Point prevalence | 1-9 / 100 000 | — | Europe | Class only |
Лекарства и терапия
Источник: Open Targets Platform (в реальном времени)
Клинические исследования
Источник: ClinicalTrials.gov (в реальном времени)