Tako-Tsubo cardiomyopathy
ORPHA:66529DiseaseUnknownAll ages
Фенотипы (HPO)37
Очень частый (80–99%)1
HP:0012663Mildly reduced ejection fraction
Частый (30–79%)5
HP:0010872T-wave inversion
HP:0012251ST segment elevation
HP:0031483Reduced contraction of the left ventricular apex
HP:0100749Chest pain
HP:0410174Increased troponin T level in blood
Периодический (5–29%)16
HP:0000822Hypertension
HP:0001513Obesity
HP:0001657Prolonged QT interval
HP:0001681Angina pectoris
HP:0001962Palpitations
HP:0002013Vomiting
HP:0002094Dyspnea
HP:0002615Hypotension
HP:0005184Prolonged QTc interval
HP:0006698Dilatation of the ventricular cavity
HP:0008180Mildly elevated creatine kinase
HP:0009805Low-output congestive heart failure
HP:0012250ST segment depression
HP:0025077Decreased QRS voltage
HP:0031138Abnormal B-type natriuretic peptide level
HP:6001073Left ventricular apical dyskinesis
Очень редкий (1–4%)11
HP:0001250Seizure
HP:0001279Syncope
HP:0001653Mitral regurgitation
HP:0001662Bradycardia
HP:0001663Ventricular fibrillation
HP:0001727Thromboembolic stroke
HP:0004308Ventricular arrhythmia
HP:0005110Atrial fibrillation
HP:0011675Arrhythmia
HP:0030149Cardiogenic shock
HP:0100598Pulmonary edema
Исключён (0%)4
HP:0001677Coronaryartery atherosclerosis
HP:0005145Coronary artery stenosis
HP:0006704Abnormal coronary artery morphology
HP:0012819Myocarditis
Эпидемиология2
| Тип оценки | Класс распространённости | Среднее (на 100к) | Регион | Квалификация |
|---|---|---|---|---|
| Point prevalence | Unknown | — | Worldwide | Class only |
| Annual incidence | 1-9 / 100 000 | 2.98 | France | Value and class |
Лекарства и терапия
Источник: Open Targets Platform (в реальном времени)
Клинические исследования
Источник: ClinicalTrials.gov (в реальном времени)