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Amoebiasis due to free-living amoebae

ORPHA:68DiseaseNot applicableAll ages

Фенотипы (68)

Частый (30–79%)13
HP:0000613Photophobia
HP:0000708Atypical behavior
HP:0000751Personality changes
HP:0001250Seizure
HP:0001945Fever
HP:0002013Vomiting
HP:0002018Nausea
HP:0002315Headache
HP:0002383Infectious encephalitis
HP:0002921Abnormality of the cerebrospinal fluid
HP:0002922Increased CSF protein concentration
HP:0200149CSF lymphocytic pleiocytosis
HP:0410263Brain imaging abnormality
Периодический (5–29%)32
HP:0000324Facial asymmetry
HP:0000572Visual loss
HP:0000651Diplopia
HP:0000711Restlessness
HP:0000737Irritability
HP:0001254Lethargy
HP:0001269Hemiparesis
HP:0001289Confusion
HP:0001317Abnormal cerebellum morphology
HP:0002134Abnormality of the basal ganglia
HP:0002143Abnormality of the spinal cord
HP:0002181Cerebral edema
HP:0002381Aphasia
HP:0002418Abnormality of midbrain morphology
HP:0002500Abnormal cerebral white matter morphology
HP:0002516Increased intracranial pressure
HP:0002538Abnormality of the cerebral cortex
HP:0002721Immunodeficiency
HP:0006897Abducens palsy
HP:0007011Fourth cranial nerve palsy
HP:0007185Loss of consciousness
HP:0007361Abnormality of the pons
HP:0010628Facial palsy
HP:0011441Abnormality of the medulla oblongata
HP:0012246Oculomotor nerve palsy
HP:0012286Abnormal hypothalamus morphology
HP:0012747Abnormal brainstem MRI signal intensity
HP:0020059Increased red blood cell count
HP:0025258Stiff neck
HP:0031179Nuchal rigidity
HP:0031910Abnormal cranial nerve physiology
HP:0032252Granuloma
Очень редкий (1–4%)23
HP:0000223Abnormality of taste sensation
HP:0000246Sinusitis
HP:0000618Blindness
HP:0000834Abnormality of the adrenal glands
HP:0001251Ataxia
HP:0001259Coma
HP:0001482Subcutaneous nodule
HP:0001700Myocardial necrosis
HP:0002090Pneumonia
HP:0004409Hyposmia
HP:0011675Arrhythmia
HP:0011947Respiratory tract infection
HP:0012804Corneal ulceration
HP:0030953Conjunctival hyperemia
HP:0031731Increased tear production
HP:0032162Unusual skin infection
HP:0032620Intrarenal abscess
HP:0040197Encephalomalacia
HP:0100583Corneal perforation
HP:0200026Ocular pain
HP:0200034Papule
HP:0200039Pustule
HP:0200042Skin ulcer

Эпидемиология (1)

Point prevalence
1-9 / 100 000
Europe

Лекарства и терапия

Источник: Open Targets Platform (в реальном времени)

Клинические исследования

Источник: ClinicalTrials.gov (в реальном времени)

Внешние ресурсы