Polyarteritis nodosa
ORPHA:767DiseaseNot applicableAll ages
Фенотипы (HPO)28
Очень частый (80–99%)1
HP:0011121Abnormal skin morphology
Частый (30–79%)10
HP:0000077Abnormality of the kidney
HP:0001824Weight loss
HP:0001945Fever
HP:0002829Arthralgia
HP:0003326Myalgia
HP:0005764Polyarticular arthritis
HP:0009830Peripheral neuropathy
HP:0011227Elevated circulating C-reactive protein concentration
HP:0031003Polyneuritis
HP:0033260Livedo racemosa
Периодический (5–29%)14
HP:0000707Abnormality of the nervous system
HP:0000822Hypertension
HP:0000965Cutis marmorata
HP:0001482Subcutaneous nodule
HP:0001701Pericarditis
HP:0002011Morphological central nervous system abnormality
HP:0002027Abdominal pain
HP:0002088Abnormal lung morphology
HP:0003390Sensory axonal neuropathy
HP:0010783Erythema
HP:0011024Abnormality of the gastrointestinal tract
HP:0030680Abnormal cardiovascular system morphology
HP:0030880Raynaud phenomenon
HP:0200042Skin ulcer
Очень редкий (1–4%)3
HP:0000478Abnormality of the eye
HP:0001638Cardiomyopathy
HP:0002102Pleuritis
Эпидемиология9
| Тип оценки | Класс распространённости | Среднее (на 100к) | Регион | Квалификация |
|---|---|---|---|---|
| Point prevalence | 1-9 / 100 000 | 3.16 | Europe | Value and class |
| Point prevalence | 1-9 / 100 000 | 3.1 | Sweden | Value and class |
| Annual incidence | 1-9 / 1 000 000 | 0.9 | United Kingdom | Value and class |
| Point prevalence | 1-9 / 100 000 | 3.07 | France | Value and class |
| Annual incidence | 1-9 / 1 000 000 | 0.11 | Australia | Value and class |
| Annual incidence | 1-9 / 1 000 000 | 0.62 | Spain | Value and class |
| Point prevalence | 1-9 / 100 000 | 3.3 | Norway | Value and class |
| Annual incidence | <1 / 1 000 000 | 0.05 | Norway | Value and class |
| Annual incidence | <1 / 1 000 000 | 0.04 | Germany | Value and class |
Лекарства и терапия
Источник: Open Targets Platform (в реальном времени)
Клинические исследования
Источник: ClinicalTrials.gov (в реальном времени)