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SAPHO syndrome

ORPHA:793DiseaseMultigenic/multifactorial, Not applicableAdolescent, Adult, Elderly

Фенотипы (30)

Очень частый (80–99%)11
HP:0000765Abnormal thorax morphology
HP:0002653Bone pain
HP:0002797Osteolysis
HP:0002829Arthralgia
HP:0005464Craniofacial osteosclerosis
HP:0010622Neoplasm of the skeletal system
HP:0100686Enthesitis
HP:0100769Synovitis
HP:0200039Pustule
HP:0100749Chest pain
HP:0100774Hyperostosis
Частый (30–79%)8
HP:0000925Abnormality of the vertebral column
HP:0000969Edema
HP:0001061Acne
HP:0001369Arthritis
HP:0002754Osteomyelitis
HP:0003765Psoriasiform dermatitis
HP:0100781Abnormality of the sacroiliac joint
HP:0100847Palmoplantar pustulosis
Периодический (5–29%)11
HP:0000988Skin rash
HP:0001581Recurrent skin infections
HP:0002024Malabsorption
HP:0002027Abdominal pain
HP:0002028Chronic diarrhea
HP:0002037Inflammation of the large intestine
HP:0002570Steatorrhea
HP:0002757Recurrent fractures
HP:0004936Venous thrombosis
HP:0006824Cranial nerve paralysis
HP:0002633Vasculitis

Эпидемиология (1)

Point prevalence
Unknown
Worldwide

Лекарства и терапия

Источник: Open Targets Platform (в реальном времени)

Клинические исследования

Источник: ClinicalTrials.gov (в реальном времени)

Внешние ресурсы