Rheumatoid factor-positive polyarticular juvenile idiopathic arthritis
ORPHA:85435DiseaseUnknownChildhood
Фенотипы (HPO)19
Очень частый (80–99%)4
HP:0001369Arthritis
HP:0002829Arthralgia
HP:0002923Rheumatoid factor positive
HP:0005764Polyarticular arthritis
Частый (30–79%)11
HP:0011117Abnormal circulating interleukin concentration
HP:0001376Limitation of joint mobility
HP:0001386Joint swelling
HP:0002813Abnormality of limb bone morphology
HP:0003565Elevated erythrocyte sedimentation rate
HP:0005187Progressive joint destruction
HP:0005930Abnormality of epiphysis morphology
HP:0006252Interphalangeal joint erosions
HP:0011227Elevated circulating C-reactive protein concentration
HP:0040311Symetrical distal arthritis
HP:0100769Synovitis
Периодический (5–29%)4
HP:0000938Osteopenia
HP:0004349Reduced bone mineral density
HP:0010588Premature epimetaphyseal fusion
HP:0100555Asymmetric growth
Эпидемиология1
| Тип оценки | Класс распространённости | Среднее (на 100к) | Регион | Квалификация |
|---|---|---|---|---|
| Point prevalence | 1-9 / 100 000 | 4.2 | Europe | Value and class |
Лекарства и терапия
Источник: Open Targets Platform (в реальном времени)
Клинические исследования
Источник: ClinicalTrials.gov (в реальном времени)