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Hereditary cerebral amyloid angiopathy

ORPHA:85458DiseaseAutosomal dominantAdult

Фенотипы (13)

Очень частый (80–99%)1
HP:0011970Cerebral amyloid angiopathy
Частый (30–79%)7
HP:0001250Seizure
HP:0001342Cerebral hemorrhage
HP:0002120Cerebral cortical atrophy
HP:0002138Subarachnoid hemorrhage
HP:0002315Headache
HP:0002344Progressive neurologic deterioration
HP:0012520Dilation of Virchow-Robin spaces
Периодический (5–29%)5
HP:0000726Dementia
HP:0002922Increased CSF protein concentration
HP:0012229CSF pleocytosis
HP:0025714Cerebral cortical microinfarct
HP:0030890Hyperintensity of cerebral white matter on MRI

Эпидемиология (2)

Cases/families
Worldwide
Point prevalence
<1 / 1 000 000
Worldwide

Лекарства и терапия

Источник: Open Targets Platform (в реальном времени)

Клинические исследования

Источник: ClinicalTrials.gov (в реальном времени)

Внешние ресурсы