Congenital toxoplasmosis

ORPHA:858DiseaseNot applicableAntenatal, Infancy, Neonatal

Фенотипы (HPO)26

Очень частый (80–99%)2

HP:0001622Premature birth

HP:0007703Abnormality of retinal pigmentation

Периодический (5–29%)24

HP:0000238Hydrocephalus

HP:0000252Microcephaly

HP:0000365Hearing impairment

HP:0000505Visual impairment

HP:0000568Microphthalmia

HP:0000639Nystagmus

HP:0000952Jaundice

HP:0001250Seizure

HP:0001252Hypotonia

HP:0001263Global developmental delay

HP:0001511Intrauterine growth retardation

HP:0001531Failure to thrive in infancy

HP:0001541Ascites

HP:0001640Cardiomegaly

HP:0001873Thrombocytopenia

HP:0001903Anemia

HP:0002014Diarrhea

HP:0002119Ventriculomegaly

HP:0002240Hepatomegaly

HP:0002514Cerebral calcification

HP:0002716Lymphadenopathy

HP:0002910Elevated circulating hepatic transaminase concentration

HP:0012733Macule

HP:0100543Cognitive impairment

Тип оценки	Класс распространённости	Среднее (на 100к)	Регион	Квалификация
Prevalence at birth	1-5 / 10 000	33	Europe	Value and class
Prevalence at birth	1-5 / 10 000	30	France	Value and class
Prevalence at birth	1-9 / 100 000	1	Greece	Value and class
Prevalence at birth	1-9 / 100 000	2.2	United Kingdom	Value and class
Prevalence at birth	1-9 / 100 000	7.3	Sweden	Value and class
Prevalence at birth	1-5 / 10 000	30	Denmark	Value and class
Prevalence at birth	1-5 / 10 000	50	Switzerland	Value and class
Prevalence at birth	>1 / 1000	130	Germany	Value and class
Prevalence at birth	>1 / 1000	113	Poland	Value and class
Prevalence at birth	1-5 / 10 000	40	Brazil	Value and class
Prevalence at birth	>1 / 1000	138	Italy	Value and class
Prevalence at birth	1-5 / 10 000	55	United States	Value and class
Point prevalence	Unknown	—	Worldwide	Class only
Prevalence at birth	>1 / 1000	640	Iran, Islamic Republic of	Value and class

Источник: Open Targets Platform (в реальном времени)

Источник: ClinicalTrials.gov (в реальном времени)