Sepsis in premature infants
ORPHA:90051Particular clinical situation in a disease or syndromeNot applicableNeonatal
Фенотипы (HPO)51
Очень частый (80–99%)5
HP:0001518Small for gestational age
HP:0001622Premature birth
HP:0001649Tachycardia
HP:0010978Abnormality of immune system physiology
HP:0040187Neonatal sepsis
Частый (30–79%)17
HP:0000980Pallor
HP:0001319Neonatal hypotonia
HP:0001875Decreased total neutrophil count
HP:0001942Metabolic acidosis
HP:0001945Fever
HP:0001974Leukocytosis
HP:0002045Hypothermia
HP:0002094Dyspnea
HP:0002579Gastrointestinal dysmotility
HP:0003270Abdominal distention
HP:0004325Decreased body weight
HP:0011227Elevated circulating C-reactive protein concentration
HP:0011410Caesarian section
HP:0012719Functional abnormality of the gastrointestinal tract
HP:0030783Increased circulating interleukin 6 concentration
HP:0031602Abnormal mucociliary clearance
HP:0032169Severe infection
Периодический (5–29%)26
HP:0000236Abnormality of the anterior fontanelle
HP:0000952Jaundice
HP:0000961Cyanosis
HP:0000967Petechiae
HP:0000969Edema
HP:0000979Purpura
HP:0001250Seizure
HP:0001265Hyporeflexia
HP:0001287Meningitis
HP:0001410Decreased liver function
HP:0001662Bradycardia
HP:0001744Splenomegaly
HP:0001873Thrombocytopenia
HP:0001892Abnormal bleeding
HP:0001903Anemia
HP:0002013Vomiting
HP:0002014Diarrhea
HP:0002240Hepatomegaly
HP:0002615Hypotension
HP:0002686Prenatal maternal abnormality
HP:0002795Abnormal respiratory system physiology
HP:0004387Enterocolitis
HP:0004713Reversible renal failure
HP:0005968Temperature instability
HP:0030863Nasal flaring
HP:0100520Oliguria
Очень редкий (1–4%)3
HP:0011880Acute disseminated intravascular coagulation
HP:0020101Invasive fungal infection
HP:0031696Disseminated viral infection
Эпидемиология1
| Тип оценки | Класс распространённости | Среднее (на 100к) | Регион | Квалификация |
|---|---|---|---|---|
| Point prevalence | 1-5 / 10 000 | 32 | Europe | Value and class |
Лекарства и терапия
Источник: Open Targets Platform (в реальном времени)
Клинические исследования
Источник: ClinicalTrials.gov (в реальном времени)