Diffuse alveolar hemorrhage
ORPHA:90060Clinical syndromeNot applicableAdolescent, Adult, Childhood, Elderly, Infancy
Фенотипы (HPO)34
Очень частый (80–99%)1
HP:0002113Pulmonary infiltrates
Частый (30–79%)8
HP:0001824Weight loss
HP:0001903Anemia
HP:0001945Fever
HP:0002105Hemoptysis
HP:0002960Autoimmunity
HP:0003565Elevated erythrocyte sedimentation rate
HP:0012735Cough
HP:0025179Ground-glass opacification on pulmonary HRCT
Периодический (5–29%)20
HP:0000093Proteinuria
HP:0000152Abnormality of head or neck
HP:0000707Abnormality of the nervous system
HP:0000790Hematuria
HP:0000924Abnormality of the skeletal system
HP:0000951Abnormality of the skin
HP:0001873Thrombocytopenia
HP:0001974Leukocytosis
HP:0002094Dyspnea
HP:0002923Rheumatoid factor positive
HP:0003259Elevated circulating creatinine concentration
HP:0003453Antineutrophil antibody positivity
HP:0003493Antinuclear antibody positivity
HP:0003613Antiphospholipid antibody positivity
HP:0004887Respiratory failure requiring assisted ventilation
HP:0005421Decreased circulating complement C3 concentration
HP:0012418Hypoxemia
HP:0045042Decreased circulating complement C4 concentration
HP:0045050Increased DLCO
HP:0100749Chest pain
Очень редкий (1–4%)5
HP:0002091Restrictive ventilatory defect
HP:0002206Pulmonary fibrosis
HP:0006536Airway obstruction
HP:0025174Irregular septal thickening on pulmonary HRCT
HP:0030950Pulmonary venous hypertension
Эпидемиология1
| Тип оценки | Класс распространённости | Среднее (на 100к) | Регион | Квалификация |
|---|---|---|---|---|
| Point prevalence | 1-9 / 100 000 | 1 | Europe | Value and class |
Лекарства и терапия
Источник: Open Targets Platform (в реальном времени)
Клинические исследования
Источник: ClinicalTrials.gov (в реальном времени)