Pauci-immune glomerulonephritis
ORPHA:93126DiseaseNot applicableAdolescent, Adult, Childhood, Elderly
Фенотипы (HPO)37
Облигатный (100%)1
HP:0000099Glomerulonephritis
Очень частый (80–99%)7
HP:0000083Renal insufficiency
HP:0000093Proteinuria
HP:0002907Microscopic hematuria
HP:0003259Elevated circulating creatinine concentration
HP:0011944Small vessel vasculitis
HP:0012213Decreased glomerular filtration rate
HP:0032230Cytoplasmic antineutrophil antibody positivity
Частый (30–79%)5
HP:0000096Glomerulosclerosis
HP:0000951Abnormality of the skin
HP:0001945Fever
HP:0002086Abnormality of the respiratory system
HP:0008653Crescentic glomerulonephritis
Периодический (5–29%)16
HP:0000478Abnormality of the eye
HP:0000979Purpura
HP:0001609Hoarse voice
HP:0001919Acute kidney injury
HP:0001970Tubulointerstitial nephritis
HP:0002027Abdominal pain
HP:0002087Abnormality of the upper respiratory tract
HP:0002094Dyspnea
HP:0002829Arthralgia
HP:0003493Antinuclear antibody positivity
HP:0004930Abnormality of the pulmonary vasculature
HP:0012089Arteritis
HP:0012587Macroscopic hematuria
HP:0012593Nephrotic range proteinuria
HP:0012735Cough
HP:0040223Pulmonary hemorrhage
Очень редкий (1–4%)6
HP:0000155Oral ulcer
HP:0001626Abnormality of the cardiovascular system
HP:0001733Pancreatitis
HP:0011024Abnormality of the gastrointestinal tract
HP:0032018Multiple mononeuropathy
HP:0100532Scleritis
Исключён (0%)2
HP:0002955Granulomatosis
HP:0032616Renal interstitial immunoglobulin deposits
Эпидемиология1
| Тип оценки | Класс распространённости | Среднее (на 100к) | Регион | Квалификация |
|---|---|---|---|---|
| Point prevalence | Unknown | — | Worldwide | Class only |
Лекарства и терапия
Источник: Open Targets Platform (в реальном времени)
Клинические исследования
Источник: ClinicalTrials.gov (в реальном времени)