Juvenile dermatomyositis
ORPHA:93672DiseaseNot applicableAdolescent, Childhood, Infancy
Фенотипы (HPO)45
Очень частый (80–99%)15
HP:0000958Dry skin
HP:0000988Skin rash
HP:0001324Muscle weakness
HP:0002960Autoimmunity
HP:0003236Elevated circulating creatine kinase concentration
HP:0003326Myalgia
HP:0003565Elevated erythrocyte sedimentation rate
HP:0003761Calcinosis
HP:0010783Erythema
HP:0011227Elevated circulating C-reactive protein concentration
HP:0012378Fatigue
HP:0100540Palpebral edema
HP:0100579Mucosal telangiectasiae
HP:0100585Telangiectasia of the skin
HP:0100614Myositis
Частый (30–79%)13
HP:0000989Pruritus
HP:0000992Cutaneous photosensitivity
HP:0001029Poikiloderma
HP:0001252Hypotonia
HP:0001369Arthritis
HP:0001596Alopecia
HP:0001945Fever
HP:0002019Constipation
HP:0002091Restrictive ventilatory defect
HP:0002633Vasculitis
HP:0002829Arthralgia
HP:0003394Muscle spasm
HP:0200042Skin ulcer
Периодический (5–29%)17
HP:0001260Dysarthria
HP:0001376Limitation of joint mobility
HP:0001609Hoarse voice
HP:0001618Dysphonia
HP:0001638Cardiomyopathy
HP:0001681Angina pectoris
HP:0001701Pericarditis
HP:0001824Weight loss
HP:0002015Dysphagia
HP:0002027Abdominal pain
HP:0002094Dyspnea
HP:0002206Pulmonary fibrosis
HP:0002239Gastrointestinal hemorrhage
HP:0003457EMG abnormality
HP:0011675Arrhythmia
HP:0011710Bundle branch block
HP:0012735Cough
Эпидемиология2
| Тип оценки | Класс распространённости | Среднее (на 100к) | Регион | Квалификация |
|---|---|---|---|---|
| Annual incidence | 1-9 / 1 000 000 | 0.295 | Worldwide | Value and class |
| Point prevalence | Unknown | — | Europe | Class only |
Лекарства и терапия
Источник: Open Targets Platform (в реальном времени)
Клинические исследования
Источник: ClinicalTrials.gov (в реальном времени)