Congenital tracheomalacia
ORPHA:95430Morphological anomalyNo data availableInfancy
Фенотипы (HPO)45
Очень частый (80–99%)2
HP:0002779Tracheomalacia
HP:0004468Anomalous tracheal cartilage
Частый (30–79%)7
HP:0001601Laryngomalacia
HP:0002093Respiratory insufficiency
HP:0002788Recurrent upper respiratory tract infections
HP:0010307Stridor
HP:0012735Cough
HP:0030828Wheezing
HP:0032355Decreased peak expiratory flow
Периодический (5–29%)20
HP:0000961Cyanosis
HP:0000973Cutis laxa
HP:0001508Failure to thrive
HP:0001609Hoarse voice
HP:0001622Premature birth
HP:0001627Abnormal heart morphology
HP:0001686Loss of voice
HP:0002020Gastroesophageal reflux
HP:0002032Esophageal atresia
HP:0002090Pneumonia
HP:0002094Dyspnea
HP:0002107Pneumothorax
HP:0002575Tracheoesophageal fistula
HP:0002643Neonatal respiratory distress
HP:0011968Feeding difficulties
HP:0012758Neurodevelopmental delay
HP:0030864Intercostal retractions
HP:0030966Abnormal pulmonary artery morphology
HP:0031245Productive cough
HP:0032177Parenchymal consolidation
Очень редкий (1–4%)16
HP:0001629Ventricular septal defect
HP:0001631Atrial septal defect
HP:0001636Tetralogy of Fallot
HP:0001640Cardiomegaly
HP:0001643Patent ductus arteriosus
HP:0001750Single ventricle
HP:0002089Pulmonary hypoplasia
HP:0002092Pulmonary arterial hypertension
HP:0002097Emphysema
HP:0002104Apnea
HP:0002110Bronchiectasis
HP:0002780Bronchomalacia
HP:0002786Tracheobronchomalacia
HP:0010773Partial anomalous pulmonary venous return
HP:0011590Double aortic arch
HP:0012020Right aortic arch
Эпидемиология1
| Тип оценки | Класс распространённости | Среднее (на 100к) | Регион | Квалификация |
|---|---|---|---|---|
| Point prevalence | Unknown | — | Europe | Class only |
Лекарства и терапия
Источник: Open Targets Platform (в реальном времени)
Клинические исследования
Источник: ClinicalTrials.gov (в реальном времени)