Post-traumatic pituitary deficiency
ORPHA:95619DiseaseAdolescent, Adult, Childhood, Elderly
Фенотипы (HPO)20
Периодический (5–29%)11
HP:0000044Hypogonadotropic hypogonadism
HP:0000141Amenorrhea
HP:0000789Infertility
HP:0000824Decreased response to growth hormone stimulation test
HP:0000938Osteopenia
HP:0001943Hypoglycemia
HP:0002615Hypotension
HP:0002920Decreased circulating ACTH level
HP:0005625Osteoporosis of vertebrae
HP:0012378Fatigue
HP:0040086Abnormal prolactin level
Очень редкий (1–4%)9
HP:0000823Delayed puberty
HP:0000863Central diabetes insipidus
HP:0000871Panhypopituitarism
HP:0001510Growth delay
HP:0002750Delayed skeletal maturation
HP:0008245Pituitary hypothyroidism
HP:0008734Decreased testicular size
HP:0009888Abnormality of secondary sexual hair
HP:0010311Aplasia/Hypoplasia of the breasts
Лекарства и терапия
Источник: Open Targets Platform (в реальном времени)
Клинические исследования
Источник: ClinicalTrials.gov (в реальном времени)