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Mosaic trisomy 8 syndrome

ORPHA:96061Malformation syndromeNot applicable, UnknownAntenatal, Infancy, Neonatal

Фенотипы (42)

Очень частый (80–99%)1
HP:0002342Intellectual disability, moderate
Частый (30–79%)27
HP:0000076Vesicoureteral reflux
HP:0000126Hydronephrosis
HP:0000268Dolichocephaly
HP:0000276Long face
HP:0000316Hypertelorism
HP:0000347Micrognathia
HP:0000377Abnormal pinna morphology
HP:0000400Macrotia
HP:0000411Protruding ear
HP:0000445Wide nose
HP:0000455Broad nasal tip
HP:0000463Anteverted nares
HP:0000486Strabismus
HP:0000490Deeply set eye
HP:0000772Abnormal rib morphology
HP:0000774Narrow chest
HP:0001376Limitation of joint mobility
HP:0001869Deep plantar creases
HP:0002007Frontal bossing
HP:0002650Scoliosis
HP:0003275Narrow pelvis bone
HP:0003422Vertebral segmentation defect
HP:0006191Deep palmar crease
HP:0006443Patellar aplasia
HP:0007957Corneal opacity
HP:0009738Abnormality of the antihelix
HP:0100490Camptodactyly of finger
Периодический (5–29%)14
HP:0000028Cryptorchidism
HP:0000098Tall stature
HP:0000175Cleft palate
HP:0000218High palate
HP:0000365Hearing impairment
HP:0000470Short neck
HP:0001010Hypopigmentation of the skin
HP:0001053Hypopigmented skin patches
HP:0001274Agenesis of corpus callosum
HP:0002804Arthrogryposis multiplex congenita
HP:0004209Clinodactyly of the 5th finger
HP:0004322Short stature
HP:0008734Decreased testicular size
HP:0030680Abnormal cardiovascular system morphology

Эпидемиология (1)

Point prevalence
Unknown
Worldwide

Лекарства и терапия

Источник: Open Targets Platform (в реальном времени)

Клинические исследования

Источник: ClinicalTrials.gov (в реальном времени)

Внешние ресурсы