GRFoma
ORPHA:97261DiseaseNot applicableAdult
Фенотипы (HPO)38
Очень частый (80–99%)1
HP:0000845Elevated circulating growth hormone concentration
Частый (30–79%)16
HP:0000280Coarse facial features
HP:0001438Abnormality of abdomen morphology
HP:0001824Weight loss
HP:0002014Diarrhea
HP:0002017Nausea and vomiting
HP:0002019Constipation
HP:0002039Anorexia
HP:0002044Zollinger-Ellison syndrome
HP:0002240Hepatomegaly
HP:0002574Episodic abdominal pain
HP:0002894Neoplasm of the pancreas
HP:0003118Increased circulating cortisol level
HP:0004396Poor appetite
HP:0007410Palmoplantar hyperhidrosis
HP:0030144Hypoactive bowel sounds
HP:0100526Neoplasm of the lung
Периодический (5–29%)19
HP:0000820Abnormality of the thyroid gland
HP:0000837Increased circulating gonadotropin level
HP:0000870Increased circulating prolactin concentration
HP:0001031Subcutaneous lipoma
HP:0001046Intermittent jaundice
HP:0001081Cholelithiasis
HP:0001406Intrahepatic cholestasis
HP:0001541Ascites
HP:0002239Gastrointestinal hemorrhage
HP:0002893Pituitary adenoma
HP:0002897Parathyroid adenoma
HP:0003072Hypercalcemia
HP:0005214Intestinal obstruction
HP:0006723Intestinal carcinoid
HP:0008200Primary hyperparathyroidism
HP:0008256Adrenocortical adenoma
HP:0012334Extrahepatic cholestasis
HP:0030145Lack of bowel sounds
HP:0100833Neoplasm of the small intestine
Очень редкий (1–4%)2
HP:0002666Pheochromocytoma
HP:0100521Neoplasm of the thymus
Эпидемиология1
| Тип оценки | Класс распространённости | Среднее (на 100к) | Регион | Квалификация |
|---|---|---|---|---|
| Point prevalence | Unknown | — | Worldwide | Class only |
Лекарства и терапия
Источник: Open Targets Platform (в реальном времени)
Клинические исследования
Источник: ClinicalTrials.gov (в реальном времени)