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Hemophilia B

ORPHA:98879DiseaseX-linked recessiveChildhood, Infancy, Neonatal

Фенотипы (14)

Очень частый (80–99%)14
HP:0000790Hematuria
HP:0001058Poor wound healing
HP:0002170Intracranial hemorrhage
HP:0003010Prolonged bleeding time
HP:0003645Prolonged partial thromboplastin time
HP:0004406Spontaneous, recurrent epistaxis
HP:0004846Prolonged bleeding after surgery
HP:0005261Joint hemorrhage
HP:0006298Prolonged bleeding after dental extraction
HP:0011858Reduced factor IX activity
HP:0012233Intramuscular hematoma
HP:0012541Cephalohematoma
HP:0040232Delayed onset bleeding
HP:0400008Menometrorrhagia

Эпидемиология (101)

Point prevalence
1-9 / 100 000
Europe
Point prevalence
1-9 / 100 000
Albania
Point prevalence
1-9 / 1 000 000
Algeria
Point prevalence
1-9 / 1 000 000
Argentina
Point prevalence
1-9 / 1 000 000
Armenia
Point prevalence
1-9 / 1 000 000
Austria
Point prevalence
1-9 / 1 000 000
Azerbaijan
Point prevalence
<1 / 1 000 000
Bangladesh
Point prevalence
1-9 / 1 000 000
Belarus
Point prevalence
1-9 / 100 000
Belgium
Point prevalence
1-9 / 100 000
Belize
Point prevalence
<1 / 1 000 000
Bolivia
Point prevalence
1-9 / 1 000 000
Bosnia and Herzegovina
Point prevalence
1-9 / 1 000 000
Brazil
Point prevalence
1-9 / 1 000 000
Bulgaria
Point prevalence
1-9 / 1 000 000
Chile
Point prevalence
1-9 / 1 000 000
Colombia
Point prevalence
1-9 / 1 000 000
Costa rica
Point prevalence
1-9 / 100 000
Croatia
Point prevalence
1-9 / 1 000 000
Cuba
Point prevalence
1-9 / 100 000
Cyprus
Point prevalence
1-9 / 100 000
Czech Republic
Point prevalence
1-9 / 100 000
Denmark
Point prevalence
1-9 / 1 000 000
Dominican Republic
Point prevalence
1-9 / 1 000 000
Ecuador
Point prevalence
1-9 / 1 000 000
Egypt
Point prevalence
1-9 / 1 000 000
El Salvador
Point prevalence
<1 / 1 000 000
Eritrea
Point prevalence
1-9 / 1 000 000
Estonia
Point prevalence
1-9 / 100 000
Finland
Point prevalence
1-9 / 1 000 000
Georgia
Point prevalence
1-9 / 1 000 000
Germany
Point prevalence
1-9 / 100 000
Greece
Point prevalence
<1 / 1 000 000
Guatemala
Point prevalence
1-9 / 1 000 000
Honduras
Point prevalence
1-9 / 100 000
Hungary
Point prevalence
1-9 / 1 000 000
Iceland
Point prevalence
<1 / 1 000 000
India
Point prevalence
<1 / 1 000 000
Indonesia
Point prevalence
1-9 / 1 000 000
Iran, Islamic Republic of
Point prevalence
1-9 / 1 000 000
Iraq
Point prevalence
1-9 / 100 000
Italy
Point prevalence
1-9 / 1 000 000
Korea, Republic of
Point prevalence
1-9 / 1 000 000
Latvia
Point prevalence
1-9 / 1 000 000
Lithuania
Point prevalence
1-9 / 1 000 000
Luxembourg
Point prevalence
1-9 / 100 000
North Macedonia
Point prevalence
1-9 / 1 000 000
Malaysia
Point prevalence
1-9 / 1 000 000
Malta
Point prevalence
1-9 / 1 000 000
Mexico
Point prevalence
1-9 / 1 000 000
Moldova, Republic of
Point prevalence
1-9 / 1 000 000
Mongolia
Point prevalence
1-9 / 1 000 000
Morocco
Point prevalence
<1 / 1 000 000
Nepal
Point prevalence
1-9 / 100 000
Netherlands
Point prevalence
1-9 / 100 000
New Zealand
Point prevalence
<1 / 1 000 000
Nigeria
Point prevalence
1-9 / 100 000
Norway
Point prevalence
1-9 / 1 000 000
Pakistan
Point prevalence
1-9 / 1 000 000
Palestinian Territory, occupied
Point prevalence
1-9 / 1 000 000
Peru
Point prevalence
1-9 / 1 000 000
Philippines
Point prevalence
1-9 / 1 000 000
Poland
Point prevalence
1-9 / 1 000 000
Portugal
Point prevalence
1-9 / 100 000
Qatar
Point prevalence
1-9 / 1 000 000
Russian Federation
Point prevalence
1-9 / 1 000 000
Saudi Arabia
Point prevalence
<1 / 1 000 000
Senegal
Point prevalence
1-9 / 1 000 000
Serbia
Point prevalence
<1 / 1 000 000
Sierra leone
Point prevalence
1-9 / 1 000 000
Singapore
Point prevalence
1-9 / 1 000 000
Israel
Point prevalence
1-9 / 1 000 000
Jamaica
Point prevalence
1-9 / 1 000 000
Jordan
Point prevalence
1-9 / 1 000 000
Kenya
Point prevalence
1-9 / 1 000 000
Lebanon
Point prevalence
1-9 / 1 000 000
Nicaragua
Point prevalence
1-9 / 1 000 000
Panama
Point prevalence
1-9 / 1 000 000
Paraguay
Point prevalence
1-9 / 1 000 000
Romania
Point prevalence
1-9 / 100 000
Slovakia
Point prevalence
1-9 / 1 000 000
Slovenia
Point prevalence
1-9 / 1 000 000
South Africa
Point prevalence
1-9 / 1 000 000
Spain
Point prevalence
<1 / 1 000 000
Sri Lanka
Point prevalence
1-9 / 1 000 000
Sudan
Point prevalence
1-9 / 100 000
Sweden
Point prevalence
1-9 / 100 000
Switzerland
Point prevalence
<1 / 1 000 000
Thailand
Point prevalence
<1 / 1 000 000
Togo
Point prevalence
1-9 / 1 000 000
Tunisia
Point prevalence
1-9 / 1 000 000
Turkey
Point prevalence
<1 / 1 000 000
Ukraine
Point prevalence
1-9 / 100 000
United Kingdom
Point prevalence
1-9 / 1 000 000
Uruguay
Point prevalence
1-9 / 1 000 000
Uzbekistan
Point prevalence
1-9 / 100 000
Venezuela
Point prevalence
1-9 / 1 000 000
Viet Nam
Point prevalence
1-9 / 1 000 000
Zimbabwe
Prevalence at birth
1-9 / 100 000
Worldwide
Point prevalence
1-9 / 100 000
France

Лекарства и терапия

Источник: Open Targets Platform (в реальном времени)

Клинические исследования

Источник: ClinicalTrials.gov (в реальном времени)

Внешние ресурсы