Abnormal origin of right or left pulmonary artery from the aorta
ORPHA:99050Morphological anomalyInfancy, Neonatal
Фенотипы (HPO)26
Очень частый (80–99%)2
HP:0005143Anomalous origin of right pulmonary artery from ascending aorta
HP:0030680Abnormal cardiovascular system morphology
Частый (30–79%)9
HP:0000961Cyanosis
HP:0001508Failure to thrive
HP:0001631Atrial septal defect
HP:0001635Congestive heart failure
HP:0001643Patent ductus arteriosus
HP:0002205Recurrent respiratory infections
HP:0002875Exertional dyspnea
HP:0012382Left-to-right shunt
HP:0032092Left ventricular outflow tract obstruction
Периодический (5–29%)9
HP:0001629Ventricular septal defect
HP:0001636Tetralogy of Fallot
HP:0001669Transposition of the great arteries
HP:0002092Pulmonary arterial hypertension
HP:0011604Aortopulmonary window
HP:0011661Anomalous origin of left pulmonary artery from ascending aorta
HP:0012303Abnormal aortic arch morphology
HP:0030148Heart murmur
HP:0031014Arteria lusoria
Очень редкий (1–4%)6
HP:0001680Coarctation of aorta
HP:0002089Pulmonary hypoplasia
HP:0004383Hypoplastic left heart
HP:0004935Pulmonary artery atresia
HP:0012020Right aortic arch
HP:0031934Abnormal descending aorta morphology
Эпидемиология2
| Тип оценки | Класс распространённости | Среднее (на 100к) | Регион | Квалификация |
|---|---|---|---|---|
| Cases/families | — | 200 | Worldwide | Case(s) |
| Point prevalence | Unknown | — | Worldwide | Class only |
Лекарства и терапия
Источник: Open Targets Platform (в реальном времени)
Клинические исследования
Источник: ClinicalTrials.gov (в реальном времени)