Atrial septal defect, coronary sinus type
ORPHA:99104Clinical subtypeAntenatal, Infancy, Neonatal
Фенотипы (HPO)26
Очень частый (80–99%)2
HP:0012382Left-to-right shunt
HP:0031297Unroofed coronary sinus
Частый (30–79%)8
HP:0001962Palpitations
HP:0002875Exertional dyspnea
HP:0003546Exercise intolerance
HP:0010772Anomalous pulmonary venous return
HP:0012378Fatigue
HP:0031634Anomalous origin of the left common carotid artery from the main pulmonary artery
HP:0031664Systolic heart murmur
HP:0031687Abnormally loud pulmonic component of the second heart sound
Периодический (5–29%)9
HP:0002092Pulmonary arterial hypertension
HP:0002094Dyspnea
HP:0002326Transient ischemic attack
HP:0005115Supraventricular arrhythmia
HP:0005133Right ventricular dilatation
HP:0011675Arrhythmia
HP:0011710Bundle branch block
HP:0030718Right atrial enlargement
HP:0031972Presyncope
Очень редкий (1–4%)7
HP:0000961Cyanosis
HP:0001279Syncope
HP:0001297Stroke
HP:0001708Right ventricular failure
HP:0002090Pneumonia
HP:0002718Recurrent bacterial infections
HP:0005317Increased pulmonary vascular resistance
Лекарства и терапия
Источник: Open Targets Platform (в реальном времени)
Клинические исследования
Источник: ClinicalTrials.gov (в реальном времени)