Crimean-Congo hemorrhagic fever
ORPHA:99827DiseaseAll ages
Фенотипы (HPO)78
Очень частый (80–99%)4
HP:0001873Thrombocytopenia
HP:0001945Fever
HP:0003496Increased circulating IgM level
HP:0030005Capillary leak
Частый (30–79%)17
HP:0000421Epistaxis
HP:0002014Diarrhea
HP:0002017Nausea and vomiting
HP:0002027Abdominal pain
HP:0002039Anorexia
HP:0002240Hepatomegaly
HP:0002315Headache
HP:0003236Elevated circulating creatine kinase concentration
HP:0003237Increased circulating IgG level
HP:0003326Myalgia
HP:0003645Prolonged partial thromboplastin time
HP:0020071Viremia
HP:0025258Stiff neck
HP:0025435Increased circulating lactate dehydrogenase concentration
HP:0030833Neck pain
HP:0032198Decreased prothrombin time
HP:0200026Ocular pain
Периодический (5–29%)30
HP:0000225Gingival bleeding
HP:0000509Conjunctivitis
HP:0000613Photophobia
HP:0000707Abnormality of the nervous system
HP:0000712Emotional lability
HP:0000713Agitation
HP:0000790Hematuria
HP:0000822Hypertension
HP:0000952Jaundice
HP:0000975Hyperhidrosis
HP:0000979Purpura
HP:0001259Coma
HP:0001262Excessive daytime somnolence
HP:0001289Confusion
HP:0001399Hepatic failure
HP:0001649Tachycardia
HP:0001662Bradycardia
HP:0001744Splenomegaly
HP:0001882Leukopenia
HP:0001974Leukocytosis
HP:0002105Hemoptysis
HP:0002248Hematemesis
HP:0002249Melena
HP:0002321Vertigo
HP:0002380Fasciculations
HP:0002615Hypotension
HP:0002716Lymphadenopathy
HP:0025143Chills
HP:0031364Ecchymosis
HP:0100247Recurrent singultus
Очень редкий (1–4%)27
HP:0000031Epididymitis
HP:0000093Proteinuria
HP:0000573Retinal hemorrhage
HP:0000846Adrenal insufficiency
HP:0001082Cholecystitis
HP:0001541Ascites
HP:0001698Pericardial effusion
HP:0001735Acute pancreatitis
HP:0001876Pancytopenia
HP:0002092Pulmonary arterial hypertension
HP:0002829Arthralgia
HP:0005162Abnormal left ventricular function
HP:0007420Spontaneous hematomas
HP:0011029Internal hemorrhage
HP:0011710Bundle branch block
HP:0011850Parotitis
HP:0011854Hemoperitoneum
HP:0011896Subconjunctival hemorrhage
HP:0011897Neutrophilia
HP:0012151Hemothorax
HP:0012219Erythema nodosum
HP:0012282Morbilliform rash
HP:0012819Myocarditis
HP:0025420Diffuse alveolar hemorrhage
HP:0031218Inappropriate antidiuretic hormone secretion
HP:0100309Subdural hemorrhage
HP:0100796Orchitis
Эпидемиология2
| Тип оценки | Класс распространённости | Среднее (на 100к) | Регион | Квалификация |
|---|---|---|---|---|
| Point prevalence | Unknown | — | Worldwide | Class only |
| Point prevalence | <1 / 1 000 000 | — | Europe | Class only |
Лекарства и терапия
Источник: Open Targets Platform (в реальном времени)
Клинические исследования
Источник: ClinicalTrials.gov (в реальном времени)