Chronic graft versus host disease
ORPHA:99921Clinical subtypeAll ages
Фенотипы (HPO)53
Очень частый (80–99%)3
HP:0001058Poor wound healing
HP:0001072Thickened skin
HP:0007432Intermittent generalized erythematous papular rash
Частый (30–79%)13
HP:0000217Xerostomia
HP:0000495Recurrent corneal erosions
HP:0000613Photophobia
HP:0001000Abnormality of skin pigmentation
HP:0001097Keratoconjunctivitis sicca
HP:0001596Alopecia
HP:0001806Onycholysis
HP:0002110Bronchiectasis
HP:0002719Recurrent infections
HP:0002910Elevated circulating hepatic transaminase concentration
HP:0008404Nail dystrophy
HP:0010783Erythema
HP:0012537Food intolerance
Периодический (5–29%)37
HP:0000142Abnormality of the vagina
HP:0000790Hematuria
HP:0001324Muscle weakness
HP:0001369Arthritis
HP:0001371Flexion contracture
HP:0001541Ascites
HP:0001741Phimosis
HP:0001824Weight loss
HP:0001876Pancytopenia
HP:0002014Diarrhea
HP:0002015Dysphagia
HP:0002018Nausea
HP:0002020Gastroesophageal reflux
HP:0002027Abdominal pain
HP:0002031Abnormal esophagus morphology
HP:0002039Anorexia
HP:0002043Esophageal stricture
HP:0002094Dyspnea
HP:0002107Pneumothorax
HP:0002113Pulmonary infiltrates
HP:0002202Pleural effusion
HP:0002829Arthralgia
HP:0003326Myalgia
HP:0004791Esophageal ulceration
HP:0006536Airway obstruction
HP:0011946Bronchiolitis obliterans
HP:0012181Entrapment neuropathy
HP:0012344Morphea
HP:0012531Pain
HP:0012735Cough
HP:0025270Abnormal esophagus physiology
HP:0030828Wheezing
HP:0100537Fasciitis
HP:0100577Urinary bladder inflammation
HP:0100749Chest pain
HP:0200037Skin vesicle
HP:0200042Skin ulcer
Лекарства и терапия
Источник: Open Targets Platform (в реальном времени)
Клинические исследования
Источник: ClinicalTrials.gov (в реальном времени)