Pemphigus vulgaris
ORPHA:704ЗаболеваниеНе применимоДетский
Фенотипы (HPO)20
Очень частый (80–99%)10
HP:0000987Atypical scarring of skin
HP:0001025Urticaria
HP:0001824Weight loss
HP:0002719Recurrent infections
HP:0002960Autoimmunity
HP:0008872Feeding difficulties in infancy
HP:0031446Erosion of oral mucosa
HP:0100792Acantholysis
HP:0100838Recurrent cutaneous abscess formation
HP:0200097Oral mucosal blisters
Частый (30–79%)7
HP:0000716Depression
HP:0000739Anxiety
HP:0008066Abnormal blistering of the skin
HP:0011968Feeding difficulties
HP:0034194Suprabasal cleavage
HP:4000013Anti-desmoglein-1 antibody positivity
HP:4000014Anti-desmoglein-3 antibody positivity
Периодический (5–29%)2
HP:0002293Alopecia of scalp
HP:0012531Pain
Очень редкий (1–4%)1
HP:0030351Urticarial plaque
Эпидемиология8
| Тип оценки | Класс распространённости | Среднее (на 100к) | Регион | Квалификация |
|---|---|---|---|---|
| Annual incidence | 1-9 / 1 000 000 | 0.13 | France | Value and class |
| Point prevalence | 1-5 / 10 000 | 18 | Europe | Value and class |
| Annual incidence | 1-9 / 1 000 000 | 0.7 | United Kingdom | Value and class |
| Annual incidence | <1 / 1 000 000 | 0.076 | Finland | Value and class |
| Annual incidence | 1-9 / 1 000 000 | 0.47 | Bulgaria | Value and class |
| Annual incidence | 1-9 / 1 000 000 | 0.42 | United States | Value and class |
| Annual incidence | 1-9 / 1 000 000 | 0.25 | Tunisia | Value and class |
| Point prevalence | 1-9 / 100 000 | 9.482 | Germany | Value and class |
Лекарства и терапия
Источник: Open Targets Platform (в реальном времени)
Клинические исследования
Источник: ClinicalTrials.gov (в реальном времени)