Neuroendocrine tumor of stomach
ORPHA:100075DiseaseNot applicableAdult, Elderly
Ассоциированные гены1
Фенотипы (HPO)32
Облигатный (100%)1
HP:0100570Carcinoid tumor
Частый (30–79%)7
HP:0001824Weight loss
HP:0001891Iron deficiency anemia
HP:0002017Nausea and vomiting
HP:0002039Anorexia
HP:0002254Intermittent diarrhea
HP:0002574Episodic abdominal pain
HP:0004396Poor appetite
Периодический (5–29%)10
HP:0001005Dermatological manifestations of systemic disorders
HP:0002044Zollinger-Ellison syndrome
HP:0002240Hepatomegaly
HP:0002248Hematemesis
HP:0002249Melena
HP:0002730Chronic noninfectious lymphadenopathy
HP:0002910Elevated circulating hepatic transaminase concentration
HP:0025085Bloody diarrhea
HP:0030145Lack of bowel sounds
HP:0030446Atypical pulmonary carcinoid tumor
Очень редкий (1–4%)14
HP:4000007Bronchoconstriction
HP:0001399Hepatic failure
HP:0001708Right ventricular failure
HP:0001962Palpitations
HP:0002615Hypotension
HP:0002668Paraganglioma
HP:0003144Increased serum serotonin
HP:0003154Increased circulating ACTH level
HP:0004385Protracted diarrhea
HP:0005180Tricuspid regurgitation
HP:0007380Facial telangiectasia
HP:0012701Bowel urgency
HP:0030149Cardiogenic shock
HP:0031566Abnormal pulmonary valve cusp morphology
Эпидемиология4
| Тип оценки | Класс распространённости | Среднее (на 100к) | Регион | Квалификация |
|---|---|---|---|---|
| Point prevalence | 1-9 / 100 000 | 3.2 | Europe | Value and class |
| Point prevalence | 1-9 / 100 000 | 1.7 | United States | Value and class |
| Point prevalence | 1-9 / 1 000 000 | 0.7 | United Kingdom | Value and class |
| Point prevalence | 1-9 / 1 000 000 | 0.5 | Japan | Value and class |
Лекарства и терапия
Источник: Open Targets Platform (в реальном времени)
Клинические исследования
Источник: ClinicalTrials.gov (в реальном времени)